Hypoxia induces expression of angiotensin‐converting enzyme II in alveolar epithelial cells: Implications for the pathogenesis of acute lung injury in COVID‐19

SARS‐CoV‐2 uptake by lung epithelial cells is a critical step in the pathogenesis of COVID‐19. Viral entry is dependent on the binding of the viral spike protein to the angiotensin converting enzyme II protein (ACE2) on the host cell surface, followed by proteolytic cleavage by a host serine proteas...

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Detalles Bibliográficos
Autores principales: Sturrock, Anne, Zimmerman, Elizabeth, Helms, My, Liou, Theodore G., Paine, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123561/
https://www.ncbi.nlm.nih.gov/pubmed/33991451
http://dx.doi.org/10.14814/phy2.14854

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