Cargando…
Identification of CRYAB(+) KCNN3(+) SOX9(+) Astrocyte-Like and EGFR(+) PDGFRA(+) OLIG1(+) Oligodendrocyte-Like Tumoral Cells in Diffuse IDH1-Mutant Gliomas and Implication of NOTCH1 Signalling in Their Genesis
SIMPLE SUMMARY: Diffuse grade II IDH-mutant gliomas are rare brain tumors mainly affecting young patients. These tumors are composed of different populations of tumoral cells. Little is known of these cells and how they are generated. These different cells may show different sensitivity to treatment...
Autores principales: | Augustus, Meera, Pineau, Donovan, Aimond, Franck, Azar, Safa, Lecca, Davide, Scamps, Frédérique, Muxel, Sophie, Darlix, Amélie, Ritchie, William, Gozé, Catherine, Rigau, Valérie, Duffau, Hugues, Hugnot, Jean-Philippe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123787/ https://www.ncbi.nlm.nih.gov/pubmed/33925547 http://dx.doi.org/10.3390/cancers13092107 |
Ejemplares similares
-
Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth
por: Leventoux, N., et al.
Publicado: (2020) -
Bevacizumab in recurrent WHO grades II–III glioma
por: Annakib, Soufyan, et al.
Publicado: (2023) -
SLUG and Truncated TAL1 Reduce Glioblastoma Stem Cell Growth Downstream of Notch1 and Define Distinct Vascular Subpopulations in Glioblastoma Multiforme
por: Guelfi, Sophie, et al.
Publicado: (2021) -
Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome
por: Chakrabarti, Lina, et al.
Publicado: (2010) -
New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development
por: Paes de Faria, Joana, et al.
Publicado: (2014)