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Pre-Senescence Induction in Hepatoma Cells Favors Hepatitis C Virus Replication and Can Be Used in Exploring Antiviral Potential of Histone Deacetylase Inhibitors

Recent evidence suggests that fibrotic liver injury in patients with chronic hepatitis C correlates with cellular senescence in damaged liver tissue. However, it is still unclear how senescence can affect replication of the hepatitis C virus (HCV). In this work, we report that an inhibitor of cyclin...

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Detalles Bibliográficos
Autores principales: Malikova, Alsu Z., Shcherbakova, Anastasia S., Konduktorov, Konstantin A., Zemskaya, Anastasia S., Dalina, Alexandra A., Popenko, Vladimir I., Leonova, Olga G., Morozov, Alexei V., Kurochkin, Nikolay N., Smirnova, Olga A., Kochetkov, Sergey N., Kozlov, Maxim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123837/
https://www.ncbi.nlm.nih.gov/pubmed/33925399
http://dx.doi.org/10.3390/ijms22094559