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Serum APOA4 Pharmacodynamically Represents Administered Recombinant Human Hepatocyte Growth Factor (E3112)

Background: Hepatocyte growth factor (HGF) is an endogenously induced bioactive molecule that has strong anti-apoptotic and tissue repair activities. In this research, we identified APOA4 as a novel pharmacodynamic (PD) marker of the recombinant human HGF (rh-HGF), E3112. Methods: rh-HGF was adminis...

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Detalles Bibliográficos
Autores principales: Motoi, Sotaro, Uesugi, Mai, Obara, Takashi, Moriya, Katsuhiro, Arita, Yoshihisa, Ogasawara, Hideaki, Soejima, Motohiro, Imai, Toshio, Kawano, Tetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123842/
https://www.ncbi.nlm.nih.gov/pubmed/33925510
http://dx.doi.org/10.3390/ijms22094578