Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources

Fatty acid amides are a diverse family of underappreciated, biologically occurring lipids. Herein, the methods for the chemical synthesis and subsequent characterization of specific members of the fatty acid amide family are described. The synthetically prepared fatty acid amides and those obtained...

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Autores principales: Ni, Ruidong, Bhandari, Suzeeta, Mitchell, Perry R., Suarez, Gabriela, Patel, Neel B., Lamb, Kara, Bisht, Kirpal S., Merkler, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123904/
https://www.ncbi.nlm.nih.gov/pubmed/33925418
http://dx.doi.org/10.3390/molecules26092543
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author Ni, Ruidong
Bhandari, Suzeeta
Mitchell, Perry R.
Suarez, Gabriela
Patel, Neel B.
Lamb, Kara
Bisht, Kirpal S.
Merkler, David J.
author_facet Ni, Ruidong
Bhandari, Suzeeta
Mitchell, Perry R.
Suarez, Gabriela
Patel, Neel B.
Lamb, Kara
Bisht, Kirpal S.
Merkler, David J.
author_sort Ni, Ruidong
collection PubMed
description Fatty acid amides are a diverse family of underappreciated, biologically occurring lipids. Herein, the methods for the chemical synthesis and subsequent characterization of specific members of the fatty acid amide family are described. The synthetically prepared fatty acid amides and those obtained commercially are used as standards for the characterization and quantification of the fatty acid amides produced by biological systems, a fatty acid amidome. The fatty acid amidomes from mouse N(18)TG(2) cells, sheep choroid plexus cells, Drosophila melanogaster, Bombyx mori, Apis mellifera, and Tribolium castaneum are presented.
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spelling pubmed-81239042021-05-16 Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources Ni, Ruidong Bhandari, Suzeeta Mitchell, Perry R. Suarez, Gabriela Patel, Neel B. Lamb, Kara Bisht, Kirpal S. Merkler, David J. Molecules Review Fatty acid amides are a diverse family of underappreciated, biologically occurring lipids. Herein, the methods for the chemical synthesis and subsequent characterization of specific members of the fatty acid amide family are described. The synthetically prepared fatty acid amides and those obtained commercially are used as standards for the characterization and quantification of the fatty acid amides produced by biological systems, a fatty acid amidome. The fatty acid amidomes from mouse N(18)TG(2) cells, sheep choroid plexus cells, Drosophila melanogaster, Bombyx mori, Apis mellifera, and Tribolium castaneum are presented. MDPI 2021-04-27 /pmc/articles/PMC8123904/ /pubmed/33925418 http://dx.doi.org/10.3390/molecules26092543 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ni, Ruidong
Bhandari, Suzeeta
Mitchell, Perry R.
Suarez, Gabriela
Patel, Neel B.
Lamb, Kara
Bisht, Kirpal S.
Merkler, David J.
Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources
title Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources
title_full Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources
title_fullStr Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources
title_full_unstemmed Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources
title_short Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources
title_sort synthesis, quantification, and characterization of fatty acid amides from in vitro and in vivo sources
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123904/
https://www.ncbi.nlm.nih.gov/pubmed/33925418
http://dx.doi.org/10.3390/molecules26092543
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