FTY720 Inhibits the Development of Collagen-Induced Arthritis in Mice by Suppressing the Recruitment of CD4(+) T Lymphocytes

BACKGROUND: Fingolimod (FTY720), a novel immunomodulator, was found to suppress the severity of collagen-induced arthritis (CIA) in mice. However, the potential molecular mechanisms are still unknown, and the effect of FTY720 on the recruitment of immune cells in the affected joints in the CIA model...

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Detalles Bibliográficos
Autores principales: Zhu, Chao, Wen, Shuang, Li, Junyong, Meng, Hongyu, Zhang, Junzhe, Zhao, Kuo, Wang, Ling, Zhang, Yingze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8123953/
https://www.ncbi.nlm.nih.gov/pubmed/34007158
http://dx.doi.org/10.2147/DDDT.S293876

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