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Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic

OBJECTIVE: The COVID-19 pandemic has forced the cancellation of planned surgery and led to significant surgical service reductions. Early intervention in aortovascular disease is often critical and cannot be deferred despite these reductions. There is urgent need to evaluate the provision and outcom...

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Autores principales: McPherson, Iain, Chilvers, Nicholas, Freystaetter, Kathrin, Sivaharan, Ashwin, Kanani, Mazyar, Williams, Robin, McCaslin, James, Nandhra, Sandip, Booth, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124015/
https://www.ncbi.nlm.nih.gov/pubmed/33905848
http://dx.doi.org/10.1016/j.avsg.2021.04.008
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author McPherson, Iain
Chilvers, Nicholas
Freystaetter, Kathrin
Sivaharan, Ashwin
Kanani, Mazyar
Williams, Robin
McCaslin, James
Nandhra, Sandip
Booth, Karen
author_facet McPherson, Iain
Chilvers, Nicholas
Freystaetter, Kathrin
Sivaharan, Ashwin
Kanani, Mazyar
Williams, Robin
McCaslin, James
Nandhra, Sandip
Booth, Karen
author_sort McPherson, Iain
collection PubMed
description OBJECTIVE: The COVID-19 pandemic has forced the cancellation of planned surgery and led to significant surgical service reductions. Early intervention in aortovascular disease is often critical and cannot be deferred despite these reductions. There is urgent need to evaluate the provision and outcomes of thoracic aortovascular intervention during the peak of the pandemic. METHODS: Prospective data was collected for patients receiving open and endovascular thoracic aortovascular intervention over two-time points; January-May 2020 and January-May 2019 at three tertiary cardiovascular centres. Baseline demographics, cardiovascular risk and COVID-19 screening results were noted. Primary outcomes were median length of intensive care unit and hospital stay, intra-operative mortality, 30-day mortality, post-operative stroke, and spinal cord injury. RESULTS: Patients operated in 2020 (41) had significantly higher median EuroSCORE II than 2019 (53) (7.44 vs. 5.86, P = 0.032) and rates of previous cardiac (19.5% vs. 3.8%, P = 0.019), aortic (14.6% vs. 1.9%, P = 0.041), and endovascular (22.0% vs. 3.8%, P = 0.009) intervention. There was an increase in proportion of urgent cases in 2020 (31.7% vs. 18.9%). There were no intra-operative deaths in 2020 and 1 in 2019 (P = 1.00). There were no significant differences (P ≥ 0.05) in 30-day mortality (4.9% vs. 13.2%), median intensive care unit length of stay (72 vs. 70 hr), median hospital length of stay (8 vs. 9 days), post-operative stroke (3 vs. 6), or spinal cord injury (2 vs. 1) between 2020 and 2019 respectively. CONCLUSIONS: Despite the increased mortality risk of patients and urgency of cases during COVID-19, complicated by the introduction of cohorting and screening regimens, thoracic aortovascular intervention remained safe with comparable in outcomes to pre-COVID-19.
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spelling pubmed-81240152021-05-17 Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic McPherson, Iain Chilvers, Nicholas Freystaetter, Kathrin Sivaharan, Ashwin Kanani, Mazyar Williams, Robin McCaslin, James Nandhra, Sandip Booth, Karen Ann Vasc Surg Covid-19 Clinical Research OBJECTIVE: The COVID-19 pandemic has forced the cancellation of planned surgery and led to significant surgical service reductions. Early intervention in aortovascular disease is often critical and cannot be deferred despite these reductions. There is urgent need to evaluate the provision and outcomes of thoracic aortovascular intervention during the peak of the pandemic. METHODS: Prospective data was collected for patients receiving open and endovascular thoracic aortovascular intervention over two-time points; January-May 2020 and January-May 2019 at three tertiary cardiovascular centres. Baseline demographics, cardiovascular risk and COVID-19 screening results were noted. Primary outcomes were median length of intensive care unit and hospital stay, intra-operative mortality, 30-day mortality, post-operative stroke, and spinal cord injury. RESULTS: Patients operated in 2020 (41) had significantly higher median EuroSCORE II than 2019 (53) (7.44 vs. 5.86, P = 0.032) and rates of previous cardiac (19.5% vs. 3.8%, P = 0.019), aortic (14.6% vs. 1.9%, P = 0.041), and endovascular (22.0% vs. 3.8%, P = 0.009) intervention. There was an increase in proportion of urgent cases in 2020 (31.7% vs. 18.9%). There were no intra-operative deaths in 2020 and 1 in 2019 (P = 1.00). There were no significant differences (P ≥ 0.05) in 30-day mortality (4.9% vs. 13.2%), median intensive care unit length of stay (72 vs. 70 hr), median hospital length of stay (8 vs. 9 days), post-operative stroke (3 vs. 6), or spinal cord injury (2 vs. 1) between 2020 and 2019 respectively. CONCLUSIONS: Despite the increased mortality risk of patients and urgency of cases during COVID-19, complicated by the introduction of cohorting and screening regimens, thoracic aortovascular intervention remained safe with comparable in outcomes to pre-COVID-19. Elsevier Inc. 2021-08 2021-04-24 /pmc/articles/PMC8124015/ /pubmed/33905848 http://dx.doi.org/10.1016/j.avsg.2021.04.008 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Covid-19 Clinical Research
McPherson, Iain
Chilvers, Nicholas
Freystaetter, Kathrin
Sivaharan, Ashwin
Kanani, Mazyar
Williams, Robin
McCaslin, James
Nandhra, Sandip
Booth, Karen
Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
title Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
title_full Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
title_fullStr Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
title_full_unstemmed Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
title_short Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
title_sort dissecting the management and outcomes of thoracic aortovascular disease during the covid-19 pandemic
topic Covid-19 Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124015/
https://www.ncbi.nlm.nih.gov/pubmed/33905848
http://dx.doi.org/10.1016/j.avsg.2021.04.008
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