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Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?

PURPOSE: To investigate pre-operative urodynamic parameters in male sling patients to ascertain whether this might better predict surgical outcomes and facilitate patient selection. METHODS: We performed a retrospective, case notes and video-urodynamics, review of men who underwent AdVanceXP male sl...

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Autores principales: Toia, Bogdan, Leung, Lap Yan, Saigal, Raveen, Solomon, Eskinder, Malde, Sachin, Taylor, Claire, Sahai, Arun, Hamid, Rizwan, Seth, Jai H., Sharma, Davendra, Greenwell, Tamsin J., Ockrim, Jeremy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124059/
https://www.ncbi.nlm.nih.gov/pubmed/32506387
http://dx.doi.org/10.1007/s00345-020-03288-8
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author Toia, Bogdan
Leung, Lap Yan
Saigal, Raveen
Solomon, Eskinder
Malde, Sachin
Taylor, Claire
Sahai, Arun
Hamid, Rizwan
Seth, Jai H.
Sharma, Davendra
Greenwell, Tamsin J.
Ockrim, Jeremy L.
author_facet Toia, Bogdan
Leung, Lap Yan
Saigal, Raveen
Solomon, Eskinder
Malde, Sachin
Taylor, Claire
Sahai, Arun
Hamid, Rizwan
Seth, Jai H.
Sharma, Davendra
Greenwell, Tamsin J.
Ockrim, Jeremy L.
author_sort Toia, Bogdan
collection PubMed
description PURPOSE: To investigate pre-operative urodynamic parameters in male sling patients to ascertain whether this might better predict surgical outcomes and facilitate patient selection. METHODS: We performed a retrospective, case notes and video-urodynamics, review of men who underwent AdVanceXP male sling in three London hospitals between 2012 and 2019. Urodynamics were performed in all centres, while retrograde leak point pressure (RLPP) was performed in one centre. RESULTS: Successful outcome was seen in 99/130 (76%) of men who required one pad or less per day. The dry rate was 51%. Pad usage was linked to worse surgical outcomes, mean 2.6 (range 1–6.5) for success vs 3.6 (range 1–10) although the ranges were wide (p = 0.002). 24 h pad weight also reached statistical significance (p = 0.05), with a mean of 181 g for success group versus 475 g for the non-successful group. The incidence of DO in the non-successful group was significantly higher than in successful group (55% versus 29%, p = 0.0009). Bladder capacity less than 250 ml was also associated with worse outcomes (p = 0.003). Reduced compliance was not correlated with outcomes (31% for success groups vs 45% for non-successful group, p = 0.15). Preoperative RLPP was performed in 60/130 patients but did not independently reach statistical significance (p = 0.25). CONCLUSION: Urodynamic parameters related to bladder function—detrusor overactivity and reduced maximum cystometric capacity predict male sling outcomes and may help in patient selection for male sling (or sphincter) surgery; whereas urodynamic parameters of sphincter incompetency (RLPP) were not predictive. Further larger scale studies are required to confirm these findings.
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spelling pubmed-81240592021-05-26 Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence? Toia, Bogdan Leung, Lap Yan Saigal, Raveen Solomon, Eskinder Malde, Sachin Taylor, Claire Sahai, Arun Hamid, Rizwan Seth, Jai H. Sharma, Davendra Greenwell, Tamsin J. Ockrim, Jeremy L. World J Urol Original Article PURPOSE: To investigate pre-operative urodynamic parameters in male sling patients to ascertain whether this might better predict surgical outcomes and facilitate patient selection. METHODS: We performed a retrospective, case notes and video-urodynamics, review of men who underwent AdVanceXP male sling in three London hospitals between 2012 and 2019. Urodynamics were performed in all centres, while retrograde leak point pressure (RLPP) was performed in one centre. RESULTS: Successful outcome was seen in 99/130 (76%) of men who required one pad or less per day. The dry rate was 51%. Pad usage was linked to worse surgical outcomes, mean 2.6 (range 1–6.5) for success vs 3.6 (range 1–10) although the ranges were wide (p = 0.002). 24 h pad weight also reached statistical significance (p = 0.05), with a mean of 181 g for success group versus 475 g for the non-successful group. The incidence of DO in the non-successful group was significantly higher than in successful group (55% versus 29%, p = 0.0009). Bladder capacity less than 250 ml was also associated with worse outcomes (p = 0.003). Reduced compliance was not correlated with outcomes (31% for success groups vs 45% for non-successful group, p = 0.15). Preoperative RLPP was performed in 60/130 patients but did not independently reach statistical significance (p = 0.25). CONCLUSION: Urodynamic parameters related to bladder function—detrusor overactivity and reduced maximum cystometric capacity predict male sling outcomes and may help in patient selection for male sling (or sphincter) surgery; whereas urodynamic parameters of sphincter incompetency (RLPP) were not predictive. Further larger scale studies are required to confirm these findings. Springer Berlin Heidelberg 2020-06-06 2021 /pmc/articles/PMC8124059/ /pubmed/32506387 http://dx.doi.org/10.1007/s00345-020-03288-8 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Toia, Bogdan
Leung, Lap Yan
Saigal, Raveen
Solomon, Eskinder
Malde, Sachin
Taylor, Claire
Sahai, Arun
Hamid, Rizwan
Seth, Jai H.
Sharma, Davendra
Greenwell, Tamsin J.
Ockrim, Jeremy L.
Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
title Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
title_full Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
title_fullStr Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
title_full_unstemmed Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
title_short Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
title_sort is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124059/
https://www.ncbi.nlm.nih.gov/pubmed/32506387
http://dx.doi.org/10.1007/s00345-020-03288-8
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