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Beraprost ameliorates postmenopausal osteoporosis by regulating Nedd4-induced Runx2 ubiquitination
Bone health requires adequate bone mass, which is maintained by a critical balance between bone resorption and formation. In our study, we identified beraprost as a pivotal regulator of bone formation and resorption. The administration of beraprost promoted differentiation of mouse bone mesenchymal...
Autores principales: | Zheng, Huo-Liang, Xu, Wen-Ning, Zhou, Wen-Sheng, Yang, Run-Ze, Chen, Peng-Bo, Liu, Tao, Jiang, Lei-Sheng, Jiang, Sheng-Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124066/ https://www.ncbi.nlm.nih.gov/pubmed/33993186 http://dx.doi.org/10.1038/s41419-021-03784-8 |
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