Cargando…
Mechanistic Modelling of Slow and Fast NHEJ DNA Repair Pathways Following Radiation for G0/G1 Normal Tissue Cells
SIMPLE SUMMARY: When cells are irradiated, their DNA can become damaged, this causes different types of repair processes to try and fix the DNA breaks. One of the most lethal types of DNA damage is double-strand breaks (DSBs). This work models the most used DSB repair process called Non-Homologous E...
Autores principales: | Qi, Yaping, Warmenhoven, John William, Henthorn, Nicholas Thomas, Ingram, Samuel Peter, Xu, Xie George, Kirkby, Karen Joy, Merchant, Michael John |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124137/ https://www.ncbi.nlm.nih.gov/pubmed/34063683 http://dx.doi.org/10.3390/cancers13092202 |
Ejemplares similares
-
Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway
por: Ingram, S. P., et al.
Publicado: (2019) -
Hi-C implementation of genome structure for in silico models of radiation-induced DNA damage
por: Ingram, Samuel P., et al.
Publicado: (2020) -
In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density
por: Henthorn, N. T., et al.
Publicado: (2018) -
Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ
por: Yu, Wei, et al.
Publicado: (2020) -
Regulation of DNA Repair pathway choice in S/G2 by the NHEJ inhibitor CYREN
por: Arnoult, Nausica, et al.
Publicado: (2017)