Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways

In Drosophila, endoplasmic reticulum (ER) stress activates the protein kinase R-like endoplasmic reticulum kinase (dPerk). dPerk can also be activated by defective mitochondria in fly models of Parkinson’s disease caused by mutations in pink1 or parkin. The Perk branch of the unfolded protein respon...

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Detalles Bibliográficos
Autores principales: Popovic, Rebeka, Celardo, Ivana, Yu, Yizhou, Costa, Ana C., Loh, Samantha H. Y., Martins, L. Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124185/
https://www.ncbi.nlm.nih.gov/pubmed/33925631
http://dx.doi.org/10.3390/ijms22094598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124185/
https://www.ncbi.nlm.nih.gov/pubmed/33925631
http://dx.doi.org/10.3390/ijms22094598

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