Hypergravity Load Modulates Acetaminophen Nephrotoxicity via Endoplasmic Reticulum Stress in Association with Hepatic microRNA-122 Expression

Hypergravity conditions may subject the kidney to intrinsic stress and lead to hemodynamic kidney dysfunction. However, the mechanisms underlying this phenomenon remain unclear. Accumulation of unfolded proteins in the endoplasmic reticulum (i.e., ER stress) is often observed in kidney diseases. The...

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Detalles Bibliográficos
Autores principales: Wu, Hong-Min, Lee, Sang-Gil, Oh, Choong-Sik, Kim, Sang-Geon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124210/
https://www.ncbi.nlm.nih.gov/pubmed/34063126
http://dx.doi.org/10.3390/ijms22094901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124210/
https://www.ncbi.nlm.nih.gov/pubmed/34063126
http://dx.doi.org/10.3390/ijms22094901

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