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Repurposing Bedaquiline for Effective Non-Small Cell Lung Cancer (NSCLC) Therapy as Inhalable Cyclodextrin-Based Molecular Inclusion Complexes

There is growing evidence that repurposed drugs demonstrate excellent efficacy against many cancers, while facilitating accelerated drug development process. In this study, bedaquiline (BDQ), an FDA approved anti-mycobacterial agent, was repurposed and an inhalable cyclodextrin complex formulation w...

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Detalles Bibliográficos
Autores principales: Parvathaneni, Vineela, Elbatanony, Rasha S., Goyal, Mimansa, Chavan, Tejashri, Vega, Nathan, Kolluru, Srikanth, Muth, Aaron, Gupta, Vivek, Kunda, Nitesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124211/
https://www.ncbi.nlm.nih.gov/pubmed/33946414
http://dx.doi.org/10.3390/ijms22094783