Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis

SIMPLE SUMMARY: The Sos Ras-GEFs are known to participate in a wide range of skin-related diseases including cutaneous cancers, cardio-facio-cutaneous syndromes, or hirsutism. However, the specific functional roles played by the Sos1 and/or Sos2 family members in specific skin compartments remain la...

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Detalles Bibliográficos
Autores principales: Baltanás, Fernando C., Mucientes-Valdivieso, Cynthia, Lorenzo-Martín, L. Francisco, Fernández-Parejo, Natalia, García-Navas, Rósula, Segrelles, Carmen, Calzada, Nuria, Fuentes-Mateos, Rocío, Paramio, Jesús M., Bustelo, Xosé R., Santos, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124217/
https://www.ncbi.nlm.nih.gov/pubmed/33946974
http://dx.doi.org/10.3390/cancers13092152

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