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Cell Shape and Matrix Stiffness Impact Schwann Cell Plasticity via YAP/TAZ and Rho GTPases

Schwann cells (SCs) are a highly plastic cell type capable of undergoing phenotypic changes following injury or disease. SCs are able to upregulate genes associated with nerve regeneration and ultimately achieve functional recovery. During the regeneration process, the extracellular matrix (ECM) and...

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Detalles Bibliográficos
Autores principales: Xu, Zhenyuan, Orkwis, Jacob A., Harris, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124465/
https://www.ncbi.nlm.nih.gov/pubmed/34062912
http://dx.doi.org/10.3390/ijms22094821

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