Cargando…

Mitochondria Turnover and Lysosomal Function in Hematopoietic Stem Cell Metabolism

Hematopoietic stem cells (HSCs) reside in a hypoxic microenvironment that enables glycolysis-fueled metabolism and reduces oxidative stress. Nonetheless, metabolic regulation in organelles such as the mitochondria and lysosomes as well as autophagic processes have been implicated as essential for th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mochizuki-Kashio, Makiko, Shiozaki, Hiroko, Suda, Toshio, Nakamura-Ishizu, Ayako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124492/ https://www.ncbi.nlm.nih.gov/pubmed/33924874 http://dx.doi.org/10.3390/ijms22094627

Ejemplares similares

Ca(2+)–mitochondria axis drives cell division in hematopoietic stem cells
por: Umemoto, Terumasa, et al.
Publicado: (2018)

Replication stress increases mitochondrial metabolism and mitophagy in FANCD2 deficient fetal liver hematopoietic stem cells
por: Mochizuki-Kashio, Makiko, et al.
Publicado: (2023)

CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow
por: Nakamura-Ishizu, Ayako, et al.
Publicado: (2015)

Correction: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow
por: Nakamura-Ishizu, Ayako, et al.
Publicado: (2015)

Thrombopoietin maintains cell numbers of hematopoietic stem and progenitor cells with megakaryopoietic potential
por: O’Neill, Aled, et al.
Publicado: (2020)

Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase
por: Nishino, Taito, et al.
Publicado: (2011)

Lysosomes and Their Role in Regulating the Metabolism of Hematopoietic Stem Cells
por: Arif, Tasleem
Publicado: (2022)

Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes
por: Oguro, Hideyuki, et al.
Publicado: (2012)

The TIF1β-HP1 System Maintains Transcriptional Integrity of Hematopoietic Stem Cells
por: Miyagi, Satoru, et al.
Publicado: (2014)

Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice
por: Wang, Changshan, et al.
Publicado: (2015)

Mitochondria and Lysosomes: Discovering Bonds
por: Todkar, Kiran, et al.
Publicado: (2017)

Suppressive Effect of LD78 on the Proliferation of Human Hemopoietic Progenitors
por: Shiozaki, Hiroko, et al.
Publicado: (1992)

Low-dose ionizing radiations leave scars on human hematopoietic stem and progenitor cells: the role of reactive oxygen species
por: Yamashita, Masayuki, et al.
Publicado: (2021)

Mitochondria: A Galaxy in the Hematopoietic and Leukemic Stem Cell Universe
por: Panuzzo, Cristina, et al.
Publicado: (2020)

Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
por: Liang, Wenjing, et al.
Publicado: (2023)

New Indications for Hematopoietic Stem Cell Gene Therapy in Lysosomal Storage Disorders
por: Rossini, Linda, et al.
Publicado: (2022)

Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization
por: Miyamoto, Kana, et al.
Publicado: (2011)

Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization
por: Miyamoto, Kana, et al.
Publicado: (2011)

Connecting lysosomes and mitochondria – a novel role for lipid metabolism in cancer cell death
por: Bartel, Karin, et al.
Publicado: (2019)

Lymphoid-biased hematopoietic stem cells and myeloid-biased hematopoietic progenitor cells have radioprotection activity
por: Zhang, Shanshan, et al.
Publicado: (2021)

Crosstalk between Lysosomes and Mitochondria in Parkinson's Disease
por: Plotegher, Nicoletta, et al.
Publicado: (2017)

Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria
por: Klein, Andrés D., et al.
Publicado: (2023)

Hematopoietic stem cell metabolism and stemness
por: Huang, Dan, et al.
Publicado: (2019)

Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
por: Chen, Fannie W., et al.
Publicado: (2022)

A culture platform to study quiescent hematopoietic stem cells following genome editing
por: Shiroshita, Kohei, et al.
Publicado: (2022)

Defining Hematopoietic Stem and Progenitor Cell Turnover by Analysis of Histone 2B-GFP Dilution
por: Foudi, Adlen, et al.
Publicado: (2008)

Lysosomes at the Crossroads of Cell Metabolism, Cell Cycle, and Stemness
por: Nowosad, Ada, et al.
Publicado: (2022)

A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
por: Chen, Qixin, et al.
Publicado: (2020)

Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes
por: Hafner Česen, M, et al.
Publicado: (2013)

Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases
por: Pijuan, Jordi, et al.
Publicado: (2022)

Fluorescent Probes Design Strategies for Imaging Mitochondria and Lysosomes
por: Chen, Huimin, et al.
Publicado: (2022)

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
por: Grumet, Lukas, et al.
Publicado: (2016)

Acquired Deficiency of A20 Results in Rapid Apoptosis, Systemic Inflammation, and Abnormal Hematopoietic Stem Cell Function
por: Nagamachi, Akiko, et al.
Publicado: (2014)

Changes in bone mineral density and bone turnover markers in patients undergoing hematopoietic stem cell transplant
por: Pandit, Aditi, et al.
Publicado: (2015)

Connecting Mitochondria, Metabolism, and Stem Cell Fate
por: Wanet, Anaïs, et al.
Publicado: (2015)

Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells
por: Takihara, Yuji, et al.
Publicado: (2022)

Metabolic Regulation of Hematopoietic Stem Cells
por: Morganti, Claudia, et al.
Publicado: (2022)

BNIP3 and NIX Mediate Mieap-Induced Accumulation of Lysosomal Proteins within Mitochondria
por: Nakamura, Yasuyuki, et al.
Publicado: (2012)

Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors
por: Yokomizo, Tomomasa, et al.
Publicado: (2019)

Mitochondria-associated ER membranes (MAMs) and lysosomal storage diseases
por: Annunziata, Ida, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tgtbeqdi76oe86uvct57qltn4t