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Intrinsically Connected: Therapeutically Targeting the Cathepsin Proteases and the Bcl-2 Family of Protein Substrates as Co-regulators of Apoptosis
Taken with the growing importance of cathepsin-mediated substrate proteolysis in tumor biology and progression, the focus and emphasis placed on therapeutic design and development is coming into fruition. Underpinning this approach is the invariable progression from the direction of fully characteri...
Autores principales: | Soond, Surinder M., Kozhevnikova, Maria V., Savvateeva, Lyudmila V., Townsend, Paul A., Zamyatnin, Andrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124540/ https://www.ncbi.nlm.nih.gov/pubmed/33925117 http://dx.doi.org/10.3390/ijms22094669 |
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