Cargando…
Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue
Dysglycemia is a public health challenge for the coming decades, especially in patients with chronic coronary syndromes (CCS). We want to assess the prevalence of undiagnosed diabetes mellitus (DM) and prediabetes, as well as identify factors associated with the development of dysglycaemia in patien...
Autores principales: | , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124594/ https://www.ncbi.nlm.nih.gov/pubmed/34063006 http://dx.doi.org/10.3390/jcm10091981 |
_version_ | 1783693252156719104 |
---|---|
author | Drobek, Natalia Sowa, Paweł Jankowski, Piotr Haberka, Maciej Gąsior, Zbigniew Kosior, Dariusz Czarnecka, Danuta Pająk, Andrzej Szostak-Janiak, Karolina Krzykwa, Agnieszka Setny, Małgorzata Kozieł, Paweł Paniczko, Marlena Jamiołkowski, Jacek Kowalska, Irina Kamiński, Karol |
author_facet | Drobek, Natalia Sowa, Paweł Jankowski, Piotr Haberka, Maciej Gąsior, Zbigniew Kosior, Dariusz Czarnecka, Danuta Pająk, Andrzej Szostak-Janiak, Karolina Krzykwa, Agnieszka Setny, Małgorzata Kozieł, Paweł Paniczko, Marlena Jamiołkowski, Jacek Kowalska, Irina Kamiński, Karol |
author_sort | Drobek, Natalia |
collection | PubMed |
description | Dysglycemia is a public health challenge for the coming decades, especially in patients with chronic coronary syndromes (CCS). We want to assess the prevalence of undiagnosed diabetes mellitus (DM) and prediabetes, as well as identify factors associated with the development of dysglycaemia in patients with CCS. In total, 1233 study participants (mean age 69 ± 9 years), who, between 6 and 18 months earlier were hospitalized for acute coronary syndrome or elective revascularization, were examined (71.4% men). The diagnosis of DM, impaired fasting glucose (IFG), impaired glucose tolerance (IGT) have been made according to World Health Organization (WHO) criteria. Based on the oral glucose tolerance test (OGTT) results, DM has been newly diagnosed in 28 (5.1%, mean age 69.9 ± 8.4 years) patients, 75% were male (n = 21). Prediabetes has been observed in 395 (72.3%) cases. IFG was found in 234 (42.9%) subjects, 161 (29.5%) individuals had IGT. According to multinomial logistic regression, body mass index (BMI) and high-density lipoprotein cholesterol (HDL-C) should be considered when assessing risk of development of dysglycaemia after discharge from the hospital. Among people with previously diagnosed DM, a significantly higher percentage were willing to change their lifestyles after the index event compared to other patients. Patients with chronic coronary syndromes suffer a very high frequency of dysglycaemia. Most patients with chronic coronary syndromes, especially those with high BMI or low HDL-C, should be considered for screening for dysglycemia using OGTT within the first year after hospitalization. A higher percentage of patients who were aware of their diabetic status changed their lifestyles, which added the benefit of timely diagnosis and treatment of diabetes. |
format | Online Article Text |
id | pubmed-8124594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81245942021-05-17 Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue Drobek, Natalia Sowa, Paweł Jankowski, Piotr Haberka, Maciej Gąsior, Zbigniew Kosior, Dariusz Czarnecka, Danuta Pająk, Andrzej Szostak-Janiak, Karolina Krzykwa, Agnieszka Setny, Małgorzata Kozieł, Paweł Paniczko, Marlena Jamiołkowski, Jacek Kowalska, Irina Kamiński, Karol J Clin Med Article Dysglycemia is a public health challenge for the coming decades, especially in patients with chronic coronary syndromes (CCS). We want to assess the prevalence of undiagnosed diabetes mellitus (DM) and prediabetes, as well as identify factors associated with the development of dysglycaemia in patients with CCS. In total, 1233 study participants (mean age 69 ± 9 years), who, between 6 and 18 months earlier were hospitalized for acute coronary syndrome or elective revascularization, were examined (71.4% men). The diagnosis of DM, impaired fasting glucose (IFG), impaired glucose tolerance (IGT) have been made according to World Health Organization (WHO) criteria. Based on the oral glucose tolerance test (OGTT) results, DM has been newly diagnosed in 28 (5.1%, mean age 69.9 ± 8.4 years) patients, 75% were male (n = 21). Prediabetes has been observed in 395 (72.3%) cases. IFG was found in 234 (42.9%) subjects, 161 (29.5%) individuals had IGT. According to multinomial logistic regression, body mass index (BMI) and high-density lipoprotein cholesterol (HDL-C) should be considered when assessing risk of development of dysglycaemia after discharge from the hospital. Among people with previously diagnosed DM, a significantly higher percentage were willing to change their lifestyles after the index event compared to other patients. Patients with chronic coronary syndromes suffer a very high frequency of dysglycaemia. Most patients with chronic coronary syndromes, especially those with high BMI or low HDL-C, should be considered for screening for dysglycemia using OGTT within the first year after hospitalization. A higher percentage of patients who were aware of their diabetic status changed their lifestyles, which added the benefit of timely diagnosis and treatment of diabetes. MDPI 2021-05-05 /pmc/articles/PMC8124594/ /pubmed/34063006 http://dx.doi.org/10.3390/jcm10091981 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Drobek, Natalia Sowa, Paweł Jankowski, Piotr Haberka, Maciej Gąsior, Zbigniew Kosior, Dariusz Czarnecka, Danuta Pająk, Andrzej Szostak-Janiak, Karolina Krzykwa, Agnieszka Setny, Małgorzata Kozieł, Paweł Paniczko, Marlena Jamiołkowski, Jacek Kowalska, Irina Kamiński, Karol Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue |
title | Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue |
title_full | Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue |
title_fullStr | Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue |
title_full_unstemmed | Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue |
title_short | Undiagnosed Diabetes and Prediabetes in Patients with Chronic Coronary Syndromes—An Alarming Public Health Issue |
title_sort | undiagnosed diabetes and prediabetes in patients with chronic coronary syndromes—an alarming public health issue |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124594/ https://www.ncbi.nlm.nih.gov/pubmed/34063006 http://dx.doi.org/10.3390/jcm10091981 |
work_keys_str_mv | AT drobeknatalia undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT sowapaweł undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT jankowskipiotr undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT haberkamaciej undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT gasiorzbigniew undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT kosiordariusz undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT czarneckadanuta undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT pajakandrzej undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT szostakjaniakkarolina undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT krzykwaagnieszka undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT setnymałgorzata undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT koziełpaweł undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT paniczkomarlena undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT jamiołkowskijacek undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT kowalskairina undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue AT kaminskikarol undiagnoseddiabetesandprediabetesinpatientswithchroniccoronarysyndromesanalarmingpublichealthissue |