Cargando…

Spatial Distribution of Private Gene Mutations in Clear Cell Renal Cell Carcinoma

SIMPLE SUMMARY: Tumours consist of multiple groups of similar cells resulting from differing evolutionary trajectories, i.e., subclones. These subclones are prevalent in clear cell renal cell carcinoma (ccRCC). The aim of this study is to determine how similar or dissimilar the subclones in 89 ccRCC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moore, Ariane L., Batavia, Aashil A., Kuipers, Jack, Singer, Jochen, Burcklen, Elodie, Schraml, Peter, Beisel, Christian, Moch, Holger, Beerenwinkel, Niko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124666/ https://www.ncbi.nlm.nih.gov/pubmed/33946379 http://dx.doi.org/10.3390/cancers13092163

Ejemplares similares

Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers
por: Hofmann, Ariane L., et al.
Publicado: (2017)

Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma()
por: Bihr, Svenja, et al.
Publicado: (2019)

Statistical tests for intra-tumour clonal co-occurrence and exclusivity
por: Kuipers, Jack, et al.
Publicado: (2021)

Loss of CDKN1A mRNA and Protein Expression Are Independent Predictors of Poor Outcome in Chromophobe Renal Cell Carcinoma Patients
por: Ohashi, Riuko, et al.
Publicado: (2020)

Next Generation Sequencing of Reactive Stroma and Residual Breast Cancer Cells in Tumor Bed after Neoadjuvant Chemotherapy
por: Varga, Zsuzsanna, et al.
Publicado: (2022)

Allele Loss and Reduced Expression of CYCLOPS Genes is a Characteristic Feature of Chromophobe Renal Cell Carcinoma
por: Ohashi, Riuko, et al.
Publicado: (2019)

Single-cell mutation calling and phylogenetic tree reconstruction with loss and recurrence
por: Kuipers, Jack, et al.
Publicado: (2022)

Single-cell mutation identification via phylogenetic inference
por: Singer, Jochen, et al.
Publicado: (2018)

Tree inference for single-cell data
por: Jahn, Katharina, et al.
Publicado: (2016)

Advances in understanding tumour evolution through single-cell sequencing()
por: Kuipers, Jack, et al.
Publicado: (2017)

Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma
por: Velagapudi, Srividya, et al.
Publicado: (2018)

VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma
por: Razafinjatovo, Caroline Fanja, et al.
Publicado: (2016)

A switch in transcription and cell fate governs the onset of an epigenetically-deregulated tumor in Drosophila
por: Torres, Joana, et al.
Publicado: (2018)

Characterization of VHL missense mutations in sporadic clear cell renal cell carcinoma: hotspots, affected binding domains, functional impact on pVHL and therapeutic relevance
por: Razafinjatovo, Caroline, et al.
Publicado: (2016)

Single-cell sequencing data reveal widespread recurrence and loss of mutational hits in the life histories of tumors
por: Kuipers, Jack, et al.
Publicado: (2017)

Discovering gene regulatory networks of multiple phenotypic groups using dynamic Bayesian networks
por: Suter, Polina, et al.
Publicado: (2022)

Quantifying cancer progression with conjunctive Bayesian networks
por: Gerstung, Moritz, et al.
Publicado: (2009)

Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data
por: Malikic, Salem, et al.
Publicado: (2019)

Single-cell phylogenies reveal changes in the evolutionary rate within cancer and healthy tissues
por: Borgsmüller, Nico, et al.
Publicado: (2023)

COMPASS: joint copy number and mutation phylogeny reconstruction from amplicon single-cell sequencing data
por: Sollier, Etienne, et al.
Publicado: (2023)

Joint inference of exclusivity patterns and recurrent trajectories from tumor mutation trees
por: Luo, Xiang Ge, et al.
Publicado: (2023)

IL‐8 and CXCR1 expression is associated with cancer stem cell‐like properties of clear cell renal cancer
por: Corrò, Claudia, et al.
Publicado: (2019)

Prognostic Immune Cell Profiling of Malignant Pleural Effusion Patients by Computerized Immunohistochemical and Transcriptional Analysis
por: Wu, Chengguang, et al.
Publicado: (2019)

Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer
por: Dondi, Arthur, et al.
Publicado: (2023)

Read length versus Depth of Coverage for Viral Quasispecies Reconstruction
por: Zagordi, Osvaldo, et al.
Publicado: (2012)

Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma
por: Dannenmann, Stefanie Regine, et al.
Publicado: (2013)

Predicting colorectal cancer risk from adenoma detection via a two-type branching process model
por: Lang, Brian M., et al.
Publicado: (2020)

Classic Chromophobe Renal Cell Carcinoma Incur a Larger Number of Chromosomal Losses Than Seen in the Eosinophilic Subtype
por: Ohashi, Riuko, et al.
Publicado: (2019)

scAmpi—A versatile pipeline for single-cell RNA-seq analysis from basics to clinics
por: Bertolini, Anne, et al.
Publicado: (2022)

An Immune Atlas of Clear Cell Renal Cell Carcinoma
por: Chevrier, Stéphane, et al.
Publicado: (2017)

Impact of differing methodologies for serum miRNA-371a-3p assessment in stage I testicular germ cell cancer recurrence
por: Christiansen, Ailsa J., et al.
Publicado: (2022)

NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis
por: Singer, Jochen, et al.
Publicado: (2018)

MiR-99b-5p expression and response to tyrosine kinase inhibitor treatment in clear cell renal cell carcinoma patients
por: Lukamowicz-Rajska, Magdalena, et al.
Publicado: (2016)

Liquid Biopsies in Renal Cell Carcinoma—Recent Advances and Promising New Technologies for the Early Detection of Metastatic Disease
por: Lakshminarayanan, Harini, et al.
Publicado: (2020)

SIEVE: joint inference of single-nucleotide variants and cell phylogeny from single-cell DNA sequencing data
por: Kang, Senbai, et al.
Publicado: (2022)

Improved pathway reconstruction from RNA interference screens by exploiting off-target effects
por: Srivatsa, Sumana, et al.
Publicado: (2018)

Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer
por: Pflueger, Dorothee, et al.
Publicado: (2015)

Homogeneous MGMT Immunoreactivity Correlates with an Unmethylated MGMT Promoter Status in Brain Metastases of Various Solid Tumors
por: Ingold, Barbara, et al.
Publicado: (2009)

Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers
por: Aimi, Fabio, et al.
Publicado: (2021)

SwissMTB: establishing comprehensive molecular cancer diagnostics in Swiss clinics
por: Singer, Franziska, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2a9dvrlobn90nkgqdnkcopfn2l