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D936Y and Other Mutations in the Fusion Core of the SARS-CoV-2 Spike Protein Heptad Repeat 1: Frequency, Geographical Distribution, and Structural Effect

The crown of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is constituted by its spike (S) glycoprotein. S protein mediates the SARS-CoV-2 entry into the host cells. The “fusion core” of the heptad repeat 1 (HR1) on S plays a crucial role in the virus infectivity, as it is part of...

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Detalles Bibliográficos
Autores principales:	Oliva, Romina, Shaikh, Abdul Rajjak, Petta, Andrea, Vangone, Anna, Cavallo, Luigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124767/ https://www.ncbi.nlm.nih.gov/pubmed/33946306 http://dx.doi.org/10.3390/molecules26092622

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