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Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite

Two-dimensional (2D) MXenes have shown a great potential for chemical sensing due to their electric properties. In this work, a Ti(3)C(2)T(x)/polypyrrole (MXene/PPy) nanocomposite has been synthesized and immobilized into a glassy carbon electrode to enable the simultaneous recognition of dopamine (...

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Autores principales: You, Qiannan, Guo, Zhongyang, Zhang, Rui, Chang, Zhimin, Ge, Mingfeng, Mei, Qian, Dong, Wen-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124802/
https://www.ncbi.nlm.nih.gov/pubmed/33924954
http://dx.doi.org/10.3390/s21093069
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author You, Qiannan
Guo, Zhongyang
Zhang, Rui
Chang, Zhimin
Ge, Mingfeng
Mei, Qian
Dong, Wen-Fei
author_facet You, Qiannan
Guo, Zhongyang
Zhang, Rui
Chang, Zhimin
Ge, Mingfeng
Mei, Qian
Dong, Wen-Fei
author_sort You, Qiannan
collection PubMed
description Two-dimensional (2D) MXenes have shown a great potential for chemical sensing due to their electric properties. In this work, a Ti(3)C(2)T(x)/polypyrrole (MXene/PPy) nanocomposite has been synthesized and immobilized into a glassy carbon electrode to enable the simultaneous recognition of dopamine (DA) and uric acid (UA) under the interference of ascorbic acid (AA). The multilayer Ti(3)C(2)T(x) MXene was prepared via the aqueous acid etching method and delaminated to a single layer nanosheet, benefiting the in-situ growth of PPy nanowires. The controllable preparation strategy and the compounding of PPy material remain great challenges for further practical application. A facile chemical oxidation method was proposed to regulate magnitude and density during the forming process of PPy nanowire, which promotes the conductivity and the electrochemical active site of this as-prepared nanomaterial. The MXene/PPy nanocomposite-modified electrode exhibited the selective determination of DA and UA in the presence of a high concentration of AA, as well as a wide linear range (DA: 12.5–125 μM, UA: 50–500 μM) and a low detection limit (DA: 0.37 μM, UA: 0.15 μM). More importantly, the simultaneous sensing for the co-existence of DA and UA was successfully achieved via the as-prepared sensor.
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spelling pubmed-81248022021-05-17 Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite You, Qiannan Guo, Zhongyang Zhang, Rui Chang, Zhimin Ge, Mingfeng Mei, Qian Dong, Wen-Fei Sensors (Basel) Communication Two-dimensional (2D) MXenes have shown a great potential for chemical sensing due to their electric properties. In this work, a Ti(3)C(2)T(x)/polypyrrole (MXene/PPy) nanocomposite has been synthesized and immobilized into a glassy carbon electrode to enable the simultaneous recognition of dopamine (DA) and uric acid (UA) under the interference of ascorbic acid (AA). The multilayer Ti(3)C(2)T(x) MXene was prepared via the aqueous acid etching method and delaminated to a single layer nanosheet, benefiting the in-situ growth of PPy nanowires. The controllable preparation strategy and the compounding of PPy material remain great challenges for further practical application. A facile chemical oxidation method was proposed to regulate magnitude and density during the forming process of PPy nanowire, which promotes the conductivity and the electrochemical active site of this as-prepared nanomaterial. The MXene/PPy nanocomposite-modified electrode exhibited the selective determination of DA and UA in the presence of a high concentration of AA, as well as a wide linear range (DA: 12.5–125 μM, UA: 50–500 μM) and a low detection limit (DA: 0.37 μM, UA: 0.15 μM). More importantly, the simultaneous sensing for the co-existence of DA and UA was successfully achieved via the as-prepared sensor. MDPI 2021-04-28 /pmc/articles/PMC8124802/ /pubmed/33924954 http://dx.doi.org/10.3390/s21093069 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
You, Qiannan
Guo, Zhongyang
Zhang, Rui
Chang, Zhimin
Ge, Mingfeng
Mei, Qian
Dong, Wen-Fei
Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite
title Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite
title_full Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite
title_fullStr Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite
title_full_unstemmed Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite
title_short Simultaneous Recognition of Dopamine and Uric Acid in the Presence of Ascorbic Acid via an Intercalated MXene/PPy Nanocomposite
title_sort simultaneous recognition of dopamine and uric acid in the presence of ascorbic acid via an intercalated mxene/ppy nanocomposite
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124802/
https://www.ncbi.nlm.nih.gov/pubmed/33924954
http://dx.doi.org/10.3390/s21093069
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