Cargando…

Rapid Screening of Glucocorticoid Receptor (GR) Effectors Using Cortisol-Detecting Sensor Cells

Cortisol, a stress hormone, plays key roles in mediating stress and anti-inflammatory responses. As abnormal cortisol levels can induce various adverse effects, screening cortisol and cortisol analogues is important for monitoring stress levels and for identifying drug candidates. A novel cell-based...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryu, Jeahee, Lee, Euiyeon, Kang, Chungwon, Lee, Minhyeong, Kim, Soyoun, Park, Seungil, Lee, Daeyeon, Kwon, Youngeun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124850/ https://www.ncbi.nlm.nih.gov/pubmed/33947115 http://dx.doi.org/10.3390/ijms22094747

Ejemplares similares

Genetically Encoded Sensor Cells for the Screening of Glucocorticoid Receptor (GR) Effectors in Herbal Extracts
por: Kang, Chungwon, et al.
Publicado: (2021)

Molecular origin of AuNPs-induced cytotoxicity and mechanistic study
por: Lee, Euiyeon, et al.
Publicado: (2019)

Systematic and mechanistic analysis of AuNP-induced nanotoxicity for risk assessment of nanomedicine
por: Lee, Euiyeon, et al.
Publicado: (2022)

Detection of Metallothionein in Javanese Medaka (Oryzias javanicus), Using a scFv-Immobilized Protein Chip
por: Lee, Euiyeon, et al.
Publicado: (2018)

Fabrication of Microarrays for the Analysis of Serological Antibody Isotypes against Food Antigens
por: Ryu, Jeahee, et al.
Publicado: (2019)

Cell-Based Sensors for the Detection of EGF and EGF-Stimulated Ca(2+) Signaling
por: Lee, Euiyeon, et al.
Publicado: (2023)

Intein-Mediated Protein Engineering for Cell-Based Biosensors
por: Kang, Chungwon, et al.
Publicado: (2022)

AHR rs4410790 genotype and IgG levels: Effect modification by lifestyle factors
por: Khil, Jaewon, et al.
Publicado: (2023)

Regulation of Melanophilin (Mlph) gene expression by the glucocorticoid receptor (GR)
por: Myung, Cheol Hwan, et al.
Publicado: (2021)

Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension in mice
por: Patel, Gaurang C., et al.
Publicado: (2018)

Expression of glucocorticoid receptor (GR) and clinical significance in adrenocortical carcinoma
por: Wu, Kan, et al.
Publicado: (2022)

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies
por: Lesovaya, Ekaterina A., et al.
Publicado: (2022)

Glucocorticoid Receptor β (GRβ): Beyond Its Dominant-Negative Function
por: Ramos-Ramírez, Patricia, et al.
Publicado: (2021)

Cortisol Rapidly Facilitates Glucocorticoid Receptor Translocation to the Plasma Membrane in Primary Trout Hepatocytes
por: Das, Chinmayee, et al.
Publicado: (2023)

Selective Glucocorticoid Receptor (GR-II) Antagonist Reduces Body Weight Gain in Mice
por: Asagami, Tomoko, et al.
Publicado: (2011)

Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo
por: Lim, Hee-Woong, et al.
Publicado: (2015)

Glucocorticoid resistance conferring mutation in the C-terminus of GR alters the receptor conformational dynamics
por: Kaziales, Anna, et al.
Publicado: (2021)

GR Dimerization and the Impact of GR Dimerization on GR Protein Stability and Half-Life
por: Louw, Ann
Publicado: (2019)

Evaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assay
por: Shafer-Weaver, Kimberly A, et al.
Publicado: (2004)

Expressions of Hippocampal Mineralocorticoid Receptor (MR) and Glucocorticoid Receptor (GR) in the Single-Prolonged Stress-Rats
por: Zhe, Du, et al.
Publicado: (2008)

P53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity
por: Zhang, Lili, et al.
Publicado: (2006)

Neuronal and Astroglial Localization of Glucocorticoid Receptor GRα in Adult Zebrafish Brain (Danio rerio)
por: Natsaridis, Evangelos, et al.
Publicado: (2023)

Impaired Spermatogenesis and gr/gr Deletions Related to Y Chromosome Haplogroups in Korean Men
por: Choi, Jin, et al.
Publicado: (2012)

The glucocorticoid receptor and cortisol levels in pediatric septic shock
por: Alder, Matthew N., et al.
Publicado: (2018)

Regulation of the kiss2 promoter in yellowtail clownfish (Amphiprion clarkii) by cortisol via GRE-dependent GR pathway
por: Bu, Shao-Yang, et al.
Publicado: (2022)

Discovery of a glucocorticoid receptor (GR) activity signature correlates with immune cell infiltration in adrenocortical carcinoma
por: Wu, Kan, et al.
Publicado: (2023)

Description of a Novel Mechanism Possibly Explaining the Antiproliferative Properties of Glucocorticoids in Duchenne Muscular Dystrophy Fibroblasts Based on Glucocorticoid Receptor GR and NFAT5
por: Herbelet, Sandrine, et al.
Publicado: (2020)

Glucocorticoid receptor (DlGR1) is expressed in pre-larval and larval stages of the teleost fish Dicentrarchus labrax
por: Di Bella, M. L., et al.
Publicado: (2008)

Icariin Improves Glucocorticoid Resistance in a Murine Model of Asthma with Depression Associated with Enhancement of GR Expression and Function
por: Jin, Hualiang, et al.
Publicado: (2022)

Group 3 innate lymphoid cells secret neutrophil chemoattractants and are insensitive to glucocorticoid via aberrant GR phosphorylation
por: He, Li Xiu, et al.
Publicado: (2023)

The nature of the GRE influences the screening for GR-activity enhancing modulators
por: Dendoncker, Karen, et al.
Publicado: (2017)

Chronic Psychosocial Stress and Negative Feedback Inhibition: Enhanced Hippocampal Glucocorticoid Signaling despite Lower Cytoplasmic GR Expression
por: Füchsl, Andrea M., et al.
Publicado: (2016)

Seminal Plasma Triggers the Differential Expression of the Glucocorticoid Receptor (NR3C1/GR) in the Rabbit Reproductive Tract
por: Ruiz-Conca, Mateo, et al.
Publicado: (2020)

Immunolocalization for glucocorticoid receptor and effect of cortisol on in vitro development of preantral follicles
por: Pontes, Julian T., et al.
Publicado: (2019)

Glucocorticoid Receptor (GR) antagonism as disease-modifying treatment for MDD with childhood trauma: protocol of the RESET-medication randomized controlled trial
por: Linsen, F., et al.
Publicado: (2023)

Gr/3D–ZnO Nanocomposites as Humidity Sensors with Enhanced Sensing Response
por: Lin, Wang-De, et al.
Publicado: (2021)

Glucocorticoid Metabolism in Hypertensive Disorders of Pregnancy: Analysis of Plasma and Urinary Cortisol and Cortisone
por: Kosicka, Katarzyna, et al.
Publicado: (2015)

Cortisol and Dexamethasone Mediate Glucocorticoid Actions in the Lesser Spotted Catshark (Scyliorhinus canicula)
por: Cabrera-Busto, Juncal, et al.
Publicado: (2021)

Glucocorticoid induced adrenal insufficiency in children: Morning cortisol values to avoid LDSST
por: Laulhé, Margaux, et al.
Publicado: (2022)

Description of the GR configuration for LEP
por: Keil, Eberhard, et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_2nrbpqrv19a1ir7fuboc3apa3q