Procaspase-Activating Compound-1 Synergizes with TRAIL to Induce Apoptosis in Established Granulosa Cell Tumor Cell Line (KGN) and Explanted Patient Granulosa Cell Tumor Cells In Vitro

Granulosa cell tumors (GCT) constitute only ~5% of ovarian neoplasms yet have significant consequences, as up to 80% of women with recurrent GCT will die of the disease. This study investigated the effectiveness of procaspase-activating compound 1 (PAC-1), an activator of procaspase-3, in treating a...

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Detalles Bibliográficos
Autores principales: Crosley, Powel, Farkkila, Anniina, Jenner, Adrianne L., Burlot, Chloé, Cardinal, Olivia, Potts, Kyle G., Agopsowicz, Kate, Pihlajoki, Marjut, Heikinheimo, Markku, Craig, Morgan, Fu, Yangxin, Hitt, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124867/
https://www.ncbi.nlm.nih.gov/pubmed/33946730
http://dx.doi.org/10.3390/ijms22094699

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