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IFN-γ Critically Enables the Intratumoural Infiltration of CXCR3(+) CD8(+) T Cells to Drive Squamous Cell Carcinoma Regression

SIMPLE SUMMARY: Cutaneous squamous cell carcinoma (SCC) is prevalent in aged individuals and individuals with compromised or weakened immune systems, indicating a close association between immune function and SCC control. The aim of our study was to uncover the identity of key immune subsets that me...

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Detalles Bibliográficos
Autores principales: Zeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H., Wells, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8124943/
https://www.ncbi.nlm.nih.gov/pubmed/33925140
http://dx.doi.org/10.3390/cancers13092131