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The PI3K/mTOR Pathway Is Targeted by Rare Germline Variants in Patients with Both Melanoma and Renal Cell Carcinoma

SIMPLE SUMMARY: Patients with malignant melanoma have an increased risk of being affected by kidney cancer and vice versa. Lifestyle risk factors contributing to these cancers differ. Instead, our study aims to assess whether common genetic predispositions may be at play. Here we reveal the clinical...

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Detalles Bibliográficos
Autores principales: Hubert, Jean-Noël, Suybeng, Voreak, Vallée, Maxime, Delhomme, Tiffany M., Maubec, Eve, Boland, Anne, Bacq, Delphine, Deleuze, Jean-François, Jouenne, Fanélie, Brennan, Paul, McKay, James D., Avril, Marie-Françoise, Bressac-de Paillerets, Brigitte, Chanudet, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125037/
https://www.ncbi.nlm.nih.gov/pubmed/34067022
http://dx.doi.org/10.3390/cancers13092243