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Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective
(1) Background: Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) emerged in Wuhan, China, in late 2019. The development of effective and safe vaccines against SARS-CoV-2 has been extremely fast. The list of orofacial adverse effects of BNT162b2 and mRNA-1273 vaccines based on the clinica...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125066/ https://www.ncbi.nlm.nih.gov/pubmed/34066995 http://dx.doi.org/10.3390/ijerph18094965 |
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author | Mazur, Marta Duś-Ilnicka, Irena Jedliński, Maciej Ndokaj, Artnora Janiszewska-Olszowska, Joanna Ardan, Roman Radwan-Oczko, Malgorzata Guerra, Fabrizio Luzzi, Valeria Vozza, Iole Marasca, Roberto Ottolenghi, Livia Polimeni, Antonella |
author_facet | Mazur, Marta Duś-Ilnicka, Irena Jedliński, Maciej Ndokaj, Artnora Janiszewska-Olszowska, Joanna Ardan, Roman Radwan-Oczko, Malgorzata Guerra, Fabrizio Luzzi, Valeria Vozza, Iole Marasca, Roberto Ottolenghi, Livia Polimeni, Antonella |
author_sort | Mazur, Marta |
collection | PubMed |
description | (1) Background: Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) emerged in Wuhan, China, in late 2019. The development of effective and safe vaccines against SARS-CoV-2 has been extremely fast. The list of orofacial adverse effects of BNT162b2 and mRNA-1273 vaccines based on the clinical trials are reported to be rare. The aim of this study was to investigate the facial and oral manifestations of COVID-19 vaccination using a survey-based study. (2) Methods: The questionnaire was developed using Google Forms and sent anonymously to a total of 700 subjects (medical personnel) in Poland, Italy, and other EU countries. (3) Results: 223 people answered the questionnaire, mainly vaccinated with BNT162b2. Only 3.1% and 5.4% experienced oral and facial symptoms, respectively. General diseases presence and age have significant influence on the probability of oral symptoms occurrence after the second dose. Facial symptoms are correlated with general disease; autoimmune pathologies and age, at first and second dose, respectively. Gender, smoking and regular medication intake have significant influence on the probability of taking an absence day. Gender, age, and smoking have a significant influence on the duration of symptoms after second dose. (4) Conclusions: Based on the results of this preliminary survey, there is no observed significant correlation between vaccine administration for COVID-19 and facial and oral manifestations. |
format | Online Article Text |
id | pubmed-8125066 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81250662021-05-17 Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective Mazur, Marta Duś-Ilnicka, Irena Jedliński, Maciej Ndokaj, Artnora Janiszewska-Olszowska, Joanna Ardan, Roman Radwan-Oczko, Malgorzata Guerra, Fabrizio Luzzi, Valeria Vozza, Iole Marasca, Roberto Ottolenghi, Livia Polimeni, Antonella Int J Environ Res Public Health Article (1) Background: Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) emerged in Wuhan, China, in late 2019. The development of effective and safe vaccines against SARS-CoV-2 has been extremely fast. The list of orofacial adverse effects of BNT162b2 and mRNA-1273 vaccines based on the clinical trials are reported to be rare. The aim of this study was to investigate the facial and oral manifestations of COVID-19 vaccination using a survey-based study. (2) Methods: The questionnaire was developed using Google Forms and sent anonymously to a total of 700 subjects (medical personnel) in Poland, Italy, and other EU countries. (3) Results: 223 people answered the questionnaire, mainly vaccinated with BNT162b2. Only 3.1% and 5.4% experienced oral and facial symptoms, respectively. General diseases presence and age have significant influence on the probability of oral symptoms occurrence after the second dose. Facial symptoms are correlated with general disease; autoimmune pathologies and age, at first and second dose, respectively. Gender, smoking and regular medication intake have significant influence on the probability of taking an absence day. Gender, age, and smoking have a significant influence on the duration of symptoms after second dose. (4) Conclusions: Based on the results of this preliminary survey, there is no observed significant correlation between vaccine administration for COVID-19 and facial and oral manifestations. MDPI 2021-05-07 /pmc/articles/PMC8125066/ /pubmed/34066995 http://dx.doi.org/10.3390/ijerph18094965 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mazur, Marta Duś-Ilnicka, Irena Jedliński, Maciej Ndokaj, Artnora Janiszewska-Olszowska, Joanna Ardan, Roman Radwan-Oczko, Malgorzata Guerra, Fabrizio Luzzi, Valeria Vozza, Iole Marasca, Roberto Ottolenghi, Livia Polimeni, Antonella Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective |
title | Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective |
title_full | Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective |
title_fullStr | Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective |
title_full_unstemmed | Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective |
title_short | Facial and Oral Manifestations Following COVID-19 Vaccination: A Survey-Based Study and a First Perspective |
title_sort | facial and oral manifestations following covid-19 vaccination: a survey-based study and a first perspective |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125066/ https://www.ncbi.nlm.nih.gov/pubmed/34066995 http://dx.doi.org/10.3390/ijerph18094965 |
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