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Inhibition of Antiviral Innate Immunity by Avibirnavirus VP3 via Blocking TBK1-TRAF3 Complex Formation and IRF3 Activation
The host innate immune system develops various strategies to antagonize virus infection, and the pathogen subverts or evades host innate immunity for self-replication. In the present study, we discovered that Avibirnavirus infectious bursal disease virus (IBDV) VP3 protein significantly inhibits MDA...
Autores principales: | Deng, Tingjuan, Hu, Boli, Wang, Xingbo, Lin, Lulu, Zhou, Jianwei, Xu, Yuting, Yan, Yan, Zheng, Xiaojuan, Zhou, Jiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125067/ https://www.ncbi.nlm.nih.gov/pubmed/33975961 http://dx.doi.org/10.1128/mSystems.00016-21 |
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