Cargando…
A Soluble Epoxide Hydrolase Inhibitor, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis
Polyunsaturated fatty acids (PUFAs) are essential FAs for human health. Cytochrome P450 oxygenates PUFAs to produce anti-inflammatory and pain-resolving epoxy fatty acids (EpFAs) and other oxylipins whose epoxide ring is opened by the soluble epoxide hydrolase (sEH/Ephx2), resulting in the formation...
Autores principales: | Jonnalagadda, Deepa, Wan, Debin, Chun, Jerold, Hammock, Bruce D., Kihara, Yasuyuki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125305/ https://www.ncbi.nlm.nih.gov/pubmed/33925035 http://dx.doi.org/10.3390/ijms22094650 |
Ejemplares similares
-
Protective Effects of the Soluble Epoxide Hydrolase Inhibitor 1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea in a Rat Model of Permanent Middle Cerebral Artery Occlusion
por: Zhang, Linlei, et al.
Publicado: (2020) -
In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea
por: Wan, Debin, et al.
Publicado: (2019) -
Soluble Epoxide Hydrolase in Atherosclerosis
por: Wang, Yi-Xin Jim, et al.
Publicado: (2010) -
Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales
por: Kitamura, Seiya, et al.
Publicado: (2017) -
Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty
Acid Amide Hydrolase Inhibitors
por: Kodani, Sean D., et al.
Publicado: (2018)