Established Beta Amyloid Pathology Is Unaffected by TREM2 Elevation in Reactive Microglia in an Alzheimer’s Disease Mouse Model

Several genetic studies have identified a rare variant of triggering receptor expressed on myeloid cells 2 (TREM2) as a risk factor for Alzheimer’s disease (AD). However, findings on the effects of TREM2 on Aβ deposition are quite inconsistent in animal studies, requiring further investigation. In t...

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Detalles Bibliográficos
Autores principales: Yuan, Qiuju, Liu, Xiaodong, Zhang, Yi, Xian, Yan-Fang, Zou, Juntao, Zhang, Xie, Huang, Pengyun, Song, You-Qiang, Lin, Zhi-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125360/
https://www.ncbi.nlm.nih.gov/pubmed/34064330
http://dx.doi.org/10.3390/molecules26092685

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