The Blockade of Tumoral IL1β-Mediated Signaling in Normal Colonic Fibroblasts Sensitizes Tumor Cells to Chemotherapy and Prevents Inflammatory CAF Activation

Heterotypic interactions between newly transformed cells and normal surrounding cells define tumor’s fate in incipient carcinomas. Once homeostasis has been lost, normal resident fibroblasts become carcinoma-associated fibroblasts, conferring protumorogenic properties on these normal cells. Here we...

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Detalles Bibliográficos
Autores principales: Díaz-Maroto, Natalia Guillén, Garcia-Vicién, Gemma, Polcaro, Giovanna, Bañuls, María, Albert, Nerea, Villanueva, Alberto, Molleví, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125420/
https://www.ncbi.nlm.nih.gov/pubmed/34066976
http://dx.doi.org/10.3390/ijms22094960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125420/
https://www.ncbi.nlm.nih.gov/pubmed/34066976
http://dx.doi.org/10.3390/ijms22094960

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