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New Estrone Oxime Derivatives: Synthesis, Cytotoxic Evaluation and Docking Studies

The interest in the introduction of the oxime group in molecules aiming to improve their biological effects is increasing. This work aimed to develop new steroidal oximes of the estrane series with potential antitumor interest. For this, several oximes were synthesized by reaction of hydroxylamine w...

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Detalles Bibliográficos
Autores principales: Canário, Catarina, Matias, Mariana, Brito, Vanessa, Santos, Adriana O., Falcão, Amílcar, Silvestre, Samuel, Alves, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125528/
https://www.ncbi.nlm.nih.gov/pubmed/34064380
http://dx.doi.org/10.3390/molecules26092687