Cargando…

Beneficial Changes in Rat Vascular Endocannabinoid System in Primary Hypertension and under Treatment with Chronic Inhibition of Fatty Acid Amide Hydrolase by URB597

Our study aimed to examine the effects of hypertension and the chronic administration of the fatty acid amide hydrolase (FAAH) inhibitor URB597 on vascular function and the endocannabinoid system in spontaneously hypertensive rats (SHR). Functional studies were performed on small mesenteric G3 arter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baranowska-Kuczko, Marta, Kozłowska, Hanna, Kloza, Monika, Harasim-Symbor, Ewa, Biernacki, Michał, Kasacka, Irena, Malinowska, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125657/ https://www.ncbi.nlm.nih.gov/pubmed/34063297 http://dx.doi.org/10.3390/ijms22094833

Ejemplares similares

Vasoprotective Endothelial Effects of Chronic Cannabidiol Treatment and Its Influence on the Endocannabinoid System in Rats with Primary and Secondary Hypertension
por: Baranowska-Kuczko, Marta, et al.
Publicado: (2021)

The FAAH Inhibitor URB597 Modulates Lipid Mediators in the Brain of Rats with Spontaneous Hypertension
por: Biernacki, Michał, et al.
Publicado: (2020)

Effect of Fatty Acid Amide Hydrolase Inhibitor URB597 on Orofacial Pain Perception in Rats
por: Zubrzycki, Marek, et al.
Publicado: (2022)

The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding
por: Sekiba, Kazuma, et al.
Publicado: (2020)

The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension
por: Biernacki, Michał, et al.
Publicado: (2018)

Vasodilatory effects of cannabidiol in human pulmonary and rat small mesenteric arteries: modification by hypertension and the potential pharmacological opportunities
por: Baranowska-Kuczko, Marta, et al.
Publicado: (2020)

Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of K(Ca)2.x and K(Ca)3.1 Channels
por: Kloza, Monika, et al.
Publicado: (2019)

Experimental Activation of Endocannabinoid System Reveals Antilipotoxic Effects on Cardiac Myocytes
por: Harasim-Symbor, Ewa, et al.
Publicado: (2020)

Acute Administration of URB597 Fatty Acid Amide Hydrolase Inhibitor Prevents Attentional Impairments by Distractors in Adolescent Mice
por: Contarini, Gabriella, et al.
Publicado: (2019)

Preservation of spatial memory and neuroprotection by the fatty acid amide hydrolase inhibitor URB597 in a rat model of vascular dementia
por: Wang, Da-Peng, et al.
Publicado: (2021)

Cannabidiol Ameliorates Monocrotaline-Induced Pulmonary Hypertension in Rats
por: Sadowska, Olga, et al.
Publicado: (2020)

Relaxation of human pulmonary arteries by PPARγ agonists
por: Kozłowska, Hanna, et al.
Publicado: (2013)

Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration
por: Biernacki, Michał, et al.
Publicado: (2017)

Cannabidiol Improves Antioxidant Capacity and Reduces Inflammation in the Lungs of Rats with Monocrotaline-Induced Pulmonary Hypertension
por: Krzyżewska, Anna, et al.
Publicado: (2022)

Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries
por: Baranowska-Kuczko, Marta, et al.
Publicado: (2014)

The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation
por: Murphy, Niamh, et al.
Publicado: (2012)

Administration of URB597, Oleoylethanolamide or Palmitoylethanolamide Increases Waking and Dopamine in Rats
por: Murillo-Rodríguez, Eric, et al.
Publicado: (2011)

Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats with Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism
por: Remiszewski, Patryk, et al.
Publicado: (2020)

Reduction of the serotonin 5-HT(1B) and 5-HT(2A) receptor-mediated contraction of human pulmonary artery by the combined 5-HT(1B) receptor antagonist and serotonin transporter inhibitor LY393558
por: Baranowska-Kuczko, Marta, et al.
Publicado: (2020)

URB597 induces subtle changes to aggression in adult Lister Hooded rats
por: Warren, William G., et al.
Publicado: (2022)

Inhibition of excessive autophagy and mitophagy mediates neuroprotective effects of URB597 against chronic cerebral hypoperfusion
por: Su, Shao-Hua, et al.
Publicado: (2018)

High-Fat Feeding in Time-Dependent Manner Affects Metabolic Routes Leading to Nervonic Acid Synthesis in NAFLD
por: Konstantynowicz-Nowicka, Karolina, et al.
Publicado: (2019)

Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety
por: Carnevali, Luca, et al.
Publicado: (2015)

The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action
por: Hamtiaux, Laurie, et al.
Publicado: (2012)

Serum sphingolipid level in psoriatic patients with obesity
por: Kozłowska, Dorota, et al.
Publicado: (2019)

Lipid profile disturbances may predispose psoriatic patients to liver dysfunction
por: Kozłowska, Dorota, et al.
Publicado: (2021)

Serum fatty acid binding protein 5 (FABP5) as a potential biomarker of inflammation in psoriasis
por: Kozłowska, Dorota, et al.
Publicado: (2021)

URB597 protects against NLRP3 inflammasome activation by inhibiting autophagy dysfunction in a rat model of chronic cerebral hypoperfusion
por: Su, Shao-Hua, et al.
Publicado: (2019)

The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity
por: Colangeli, Roberto, et al.
Publicado: (2017)

Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibitor URB597 Against Oxygen–Glucose Deprivation-Induced Ischemic Neuronal Injury
por: Wang, Da-Peng, et al.
Publicado: (2021)

Cannabinoids—A New Perspective in Adjuvant Therapy for Pulmonary Hypertension
por: Krzyżewska, Anna, et al.
Publicado: (2021)

The endocannabinoid hydrolase FAAH is an allosteric enzyme
por: Dainese, Enrico, et al.
Publicado: (2020)

Author Correction: The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity
por: Colangeli, Roberto, et al.
Publicado: (2018)

Author Correction: The FAAH inhibitor URB597 suppresses hippocampal maximal dentate afterdischarges and restores seizure-induced impairment of short and long-term synaptic plasticity
por: Colangeli, Roberto, et al.
Publicado: (2018)

Arte urbe /
Publicado: (2009)

Urbe fugitiva /
por: Musacchio, Humberto, 1943-
Publicado: (2002)

Urbs in Rure
Publicado: (1910)

GPR18-Mediated Relaxation of Human Isolated Pulmonary Arteries
por: Kozłowska, Hanna, et al.
Publicado: (2022)

The activity of the endocannabinoid metabolising enzyme fatty acid amide hydrolase in subcutaneous adipocytes correlates with BMI in metabolically healthy humans
por: Cable, Jemma C, et al.
Publicado: (2011)

Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling
por: Bartoll, Adrián, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6ckn7dopf1623pk4s03q4dcpn5