Cargando…
Characterization of the HCN Interaction Partner TRIP8b/PEX5R in the Intracardiac Nervous System of TRIP8b-Deficient and Wild-Type Mice
The tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b/PEX5R) is an interaction partner and auxiliary subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, which are key for rhythm generation in the brain and in the heart. Since TRIP8b is expressed in cent...
Autores principales: | Scherschel, Katharina, Bräuninger, Hanna, Mölders, Andrea, Erlenhardt, Nadine, Amin, Ehsan, Jungen, Christiane, Pape, Ulrike, Lindner, Diana, Chetkovich, Dane M., Klöcker, Nikolaj, Meyer, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125662/ https://www.ncbi.nlm.nih.gov/pubmed/33946275 http://dx.doi.org/10.3390/ijms22094772 |
Ejemplares similares
-
TRIP8b Is Required for Maximal Expression of HCN1 in the Mouse Retina
por: Pan, Yuan, et al.
Publicado: (2014) -
Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels
por: Zobeiri, Mehrnoush, et al.
Publicado: (2017) -
Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons
por: Han, Ye, et al.
Publicado: (2022) -
HCN channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects
por: Han, Ye, et al.
Publicado: (2016) -
Regulation of Axonal HCN1 Trafficking in Perforant Path Involves Expression of Specific TRIP8b Isoforms
por: Wilkars, Wiebke, et al.
Publicado: (2012)