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Ceramide Synthase 6 Maximizes p53 Function to Prevent Progeny Formation from Polyploid Giant Cancer Cells
SIMPLE SUMMARY: One mechanism that contributes to cancer recurrence is the ability of some malignant cells to temporarily halt cell division and accumulate multiple nuclei that are later released as progeny, which resume cell division. The release of progeny occurs via primitive cleavage and is high...
Autores principales: | Lu, Ping, White-Gilbertson, Shai, Beeson, Gyda, Beeson, Craig, Ogretmen, Besim, Norris, James, Voelkel-Johnson, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125704/ https://www.ncbi.nlm.nih.gov/pubmed/34062962 http://dx.doi.org/10.3390/cancers13092212 |
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