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High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications
A generalization of the concept of multimode interference sensors is presented here for the first time, to the best of our knowledge. The existing bimodal and trimodal sensors correspond to particular cases of those interference sensors. A thorough study of the properties of the multimode waveguide...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125838/ https://www.ncbi.nlm.nih.gov/pubmed/34066692 http://dx.doi.org/10.3390/s21093254 |
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author | Isayama, Yuri Hayashi Hernández-Figueroa, Hugo Enrique |
author_facet | Isayama, Yuri Hayashi Hernández-Figueroa, Hugo Enrique |
author_sort | Isayama, Yuri Hayashi |
collection | PubMed |
description | A generalization of the concept of multimode interference sensors is presented here for the first time, to the best of our knowledge. The existing bimodal and trimodal sensors correspond to particular cases of those interference sensors. A thorough study of the properties of the multimode waveguide section provided a deeper insight into the behavior of this class of sensors, which allowed us to establish new criteria for designing more sensitive structures. Other challenges of using high-order modes within the sensing area of the device reside in the excitation of these modes and the interpretation of the output signal. To overcome these, we developed a novel structure to excite any desired high-order mode along with the fundamental mode within the sensing section, while maintaining a fine control over the power distribution between them. A new strategy to detect and interpret the output signal is also presented in detail. Finally, we designed a high-order sensor for which numerical simulations showed a theoretical limit of detection of [Formula: see text] RIU, making this device the most sensitive multimode interference sensor reported so far. |
format | Online Article Text |
id | pubmed-8125838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81258382021-05-17 High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications Isayama, Yuri Hayashi Hernández-Figueroa, Hugo Enrique Sensors (Basel) Article A generalization of the concept of multimode interference sensors is presented here for the first time, to the best of our knowledge. The existing bimodal and trimodal sensors correspond to particular cases of those interference sensors. A thorough study of the properties of the multimode waveguide section provided a deeper insight into the behavior of this class of sensors, which allowed us to establish new criteria for designing more sensitive structures. Other challenges of using high-order modes within the sensing area of the device reside in the excitation of these modes and the interpretation of the output signal. To overcome these, we developed a novel structure to excite any desired high-order mode along with the fundamental mode within the sensing section, while maintaining a fine control over the power distribution between them. A new strategy to detect and interpret the output signal is also presented in detail. Finally, we designed a high-order sensor for which numerical simulations showed a theoretical limit of detection of [Formula: see text] RIU, making this device the most sensitive multimode interference sensor reported so far. MDPI 2021-05-08 /pmc/articles/PMC8125838/ /pubmed/34066692 http://dx.doi.org/10.3390/s21093254 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Isayama, Yuri Hayashi Hernández-Figueroa, Hugo Enrique High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications |
title | High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications |
title_full | High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications |
title_fullStr | High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications |
title_full_unstemmed | High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications |
title_short | High-Order Multimode Waveguide Interferometer for Optical Biosensing Applications |
title_sort | high-order multimode waveguide interferometer for optical biosensing applications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125838/ https://www.ncbi.nlm.nih.gov/pubmed/34066692 http://dx.doi.org/10.3390/s21093254 |
work_keys_str_mv | AT isayamayurihayashi highordermultimodewaveguideinterferometerforopticalbiosensingapplications AT hernandezfigueroahugoenrique highordermultimodewaveguideinterferometerforopticalbiosensingapplications |