Cargando…

Synthesis, Characterization, and Preliminary In Vitro Cytotoxic Evaluation of a Series of 2-Substituted Benzo [d] [1,3] Azoles

A series of benzo [d] [1,3] azoles 2-substituted with benzyl- and allyl-sulfanyl groups were synthesized, and their cytotoxic activities were in vitro evaluated against a panel of six human cancer cell lines. The results showed that compounds BTA-1 and BMZ-2 have the best inhibitory effects, compoun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linares-Anaya, Ozvaldo, Avila-Sorrosa, Alcives, Díaz-Cedillo, Francisco, Gil-Ruiz, Luis Ángel, Correa-Basurto, José, Salazar-Mendoza, Domingo, Orjuela, Adrian L., Alí-Torres, Jorge, Ramírez-Apan, María Teresa, Morales-Morales, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125891/ https://www.ncbi.nlm.nih.gov/pubmed/34066820 http://dx.doi.org/10.3390/molecules26092780

Ejemplares similares

3-[1-(3-Hydroxybenzyl)-1H-benzimidazol-2-yl]phenol dimethyl sulfoxide monosolvate
por: Quezada-Miriel, Magdalena, et al.
Publicado: (2012)

1-Ethenyl-4-[(phenylsulfanyl)methyl]benzene
por: Avila-Sorrosa, Alcives, et al.
Publicado: (2012)

[2-(Diphenylphosphanyl)benzenethiolato-κ(2) P,S](pyridine-2-thiolato-κS)(triphenylphosphine-κP)palladium(II)
por: Ríos-Sanchez, Raúl, et al.
Publicado: (2010)

trans-Chlorido(4-fluorobenzenethiolato-κS)bis(triphenylphosphane-κP)palladium(II) methanol hemisolvate
por: Avila-Sorrosa, Alcives, et al.
Publicado: (2014)

Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents
por: Avila-Sorrosa, Alcives, et al.
Publicado: (2019)

trans-Bis(μ-benzenethiolato-κ(2) S:S)bis[chlorido(triphenylphosphane-κP)palladium(II)] chloroform disolvate
por: Avila-Sorrosa, Alcives, et al.
Publicado: (2013)

Mechanochemistry: A Green Approach in the Preparation of Pharmaceutical Cocrystals
por: Solares-Briones, Mizraín, et al.
Publicado: (2021)

Relevance of Fluorinated Ligands to the Design of Metallodrugs for Their Potential Use in Cancer Treatment
por: Páez-Franco, José C., et al.
Publicado: (2022)

Synthesis of Non-Cytotoxic Poly(Ester-Amine) Dendrimers as Potential Solubility Enhancers for Drugs: Methotrexate as a Case Study
por: Soto-Castro, Delia, et al.
Publicado: (2010)

Diverse N-Substituted Azole-Containing Amino Acids as Building Blocks for Cyclopeptides
por: Motevalli, Somayeh, et al.
Publicado: (2020)

Preliminary Anticonvulsant and Toxicity Screening of Substituted Benzylidenehydrazinyl-N-(6-substituted benzo[d]thiazol-2-yl)propanamides
por: Ali, Ruhi, et al.
Publicado: (2014)

Preparation of Chiral Enantioenriched Densely Substituted Cyclopropyl Azoles, Amines, and Ethers via Formal S(N)2′ Substitution of Bromocylopropanes
por: Straub, Hillary, et al.
Publicado: (2022)

Donor-Acceptor Substituted Benzo-, Naphtho- and Phenanthro-Fused Norbornadienes
por: Mansø, Mads, et al.
Publicado: (2020)

Supramolecular-induced regiocontrol over the photochemical [4 + 4] cyclodimerization of NHC- or azole-substituted anthracenes
por: Bai, Sha, et al.
Publicado: (2020)

First Gallium and Indium Crystal Structures of Curcuminoid Homoleptic Complexes: All-Different Ligand Stereochemistry and Cytotoxic Potential
por: Meza-Morales, William, et al.
Publicado: (2023)

The carcinogenicity of some 6-substituted benzo(a)pyrene derivatives in mice.
por: Dewhurst, F., et al.
Publicado: (1972)

Oxidative Stress, Cytotoxic and Inflammatory Effects of Azoles Combinatorial Mixtures in Sertoli TM4 Cells
por: Petricca, Sabrina, et al.
Publicado: (2023)

Synthesis and Antitumor Evaluation of 6-Aryl-substituted benzo[j]phenanthridine- and Benzo[g]pyrimido[4,5-c]isoquinolinequinones
por: Iribarra, Jennyfer, et al.
Publicado: (2012)

A Preliminary in vitro and in vivo Evaluation of the Effect and Action Mechanism of 17-AAG Combined With Azoles Against Azole-Resistant Candida spp.
por: Liu, Luyao, et al.
Publicado: (2022)

3-Aminopyridin-1-ium 3-carboxybenzoate
por: Campos-Gaxiola, Jose J., et al.
Publicado: (2012)

Antibacterial Activities of Azole Complexes Combined with Silver Nanoparticles
por: Bello-Vieda, Nestor J., et al.
Publicado: (2018)

Development of Azole Resistance in Aspergillus fumigatus during Azole Therapy Associated with Change in Virulence
por: Arendrup, Maiken Cavling, et al.
Publicado: (2010)

Imidazolyl‐Substituted Benzo‐ and Naphthodithiophenes as Precursors for the Synthesis of Transient Open‐Shell Quinoids
por: Hou, Peng, et al.
Publicado: (2023)

Full Structural Characterization of Homoleptic Complexes of Diacetylcurcumin with Mg, Zn, Cu, and Mn: Cisplatin-level Cytotoxicity in Vitro with Minimal Acute Toxicity in Vivo
por: Meza-Morales, William, et al.
Publicado: (2019)

Azole potentiation in Candida species
por: Stenkiewicz-Witeska, Jan S., et al.
Publicado: (2023)

Development of cross-resistance by Aspergillus fumigatus to clinical azoles following exposure to prochloraz, an agricultural azole
por: Faria-Ramos, Isabel, et al.
Publicado: (2014)

In vitro interaction of isavuconazole and anidulafungin against azole-susceptible and azole-resistant Aspergillus fumigatus isolates
por: Buil, J B, et al.
Publicado: (2020)

P060 A preliminary in vitro and in vivo evaluation of the effect and action mechanism of 17-AAG combined with azoles against azole-resistant Candida spp.
por: Liu, Md Luyao
Publicado: (2022)

Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase
por: Caramalho, Rita, et al.
Publicado: (2017)

Implication of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Its Inhibitors in Alzheimer’s Disease Murine Models
por: Fragoso-Morales, Leticia Guadalupe, et al.
Publicado: (2021)

Synthesis of Nonsymmetrically Substituted 2,3-Dialkoxyphenazine Derivatives and Preliminary Examination of Their Cytotoxicity
por: Ręka, Paweł, et al.
Publicado: (2023)

Azole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?
por: Verweij, Paul E., et al.
Publicado: (2016)

The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions
por: Warrilow, Andrew G., et al.
Publicado: (2019)

Azole-Resistant Aspergillus fumigatus, Iran
por: Seyedmousavi, Seyedmojtaba, et al.
Publicado: (2013)

Diazocarbonyl and Related Compounds in the Synthesis of Azoles
por: Budeev, Anton, et al.
Publicado: (2021)

New Antifungal Agents with Azole Moieties
por: Teixeira, Melissa Martins, et al.
Publicado: (2022)

Invasive Aspergillosis and the Impact of Azole-resistance
por: Bosetti, Davide, et al.
Publicado: (2023)

Chemical characterization (LC–MS–ESI), cytotoxic activity and intracellular localization of PAMAM G4 in leukemia cells
por: Flores-Mejía, R., et al.
Publicado: (2021)

Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance
por: Kim, Sang Hu, et al.
Publicado: (2019)

Synthesis and anti-tubercular activity of 3-substituted benzo[b]thiophene-1,1-dioxides
por: Chandrasekera, N. Susantha, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k6shp2ipvd00iu612hqu5pjg4l