A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches

Nucleotide excision repair (NER) resolves DNA adducts, such as those caused by ultraviolet light. Deficient NER (dNER) results in a higher mutation rate that can predispose to cancer development and premature ageing phenotypes. Here, we used isogenic dNER model cell lines to establish a gene express...

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Detalles Bibliográficos
Autores principales: Wei, Rongbin, Dai, Hui, Zhang, Jing, Shih, David J. H., Liang, Yulong, Xiao, Pengfeng, McGrail, Daniel J., Lin, Shiaw-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125907/
https://www.ncbi.nlm.nih.gov/pubmed/34066883
http://dx.doi.org/10.3390/ijms22095008

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