Cargando…

PlatyphyllenoneExerts Anti-Metastatic Effects on Human Oral Cancer Cells by Modulating Cathepsin L Expression, MAPK Pathway and Epithelial–Mesenchymal Transition

Advanced-stage oral cancers with lymph node metastasis are associated with poor prognosis and a high mortality rate. Although recent advancement in cancer treatment has effectively improved the oral cancer prognosis, the majority of therapeutic interventions are highly expensive and are associated w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bharath Kumar, V., Lin, Jen-Tsun, Mahalakshmi, B., Chuang, Yi-Ching, Ho, Hsin-Yu, Lin, Chia-Chieh, Lo, Yu-Sheng, Hsieh, Ming-Ju, Chen, Mu-Kuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125947/ https://www.ncbi.nlm.nih.gov/pubmed/34065077 http://dx.doi.org/10.3390/ijms22095012

Ejemplares similares

Platyphyllenone Induces Autophagy and Apoptosis by Modulating the AKT and JNK Mitogen-Activated Protein Kinase Pathways in Oral Cancer Cells
por: Liu, Yen-Tze, et al.
Publicado: (2021)

Luteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway
por: Velmurugan, Bharath Kumar, et al.
Publicado: (2020)

7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway
por: Kumar, V. Bharath, et al.
Publicado: (2021)

Shuterin Enhances the Cytotoxicity of the Natural Killer Leukemia Cell Line KHYG-1 by Increasing the Expression Levels of Granzyme B and IFN-γ through the MAPK and Ras/Raf Signaling Pathways
por: Lin, Jen-Tsun, et al.
Publicado: (2022)

Inhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways
por: Hsieh, Ming-Ju, et al.
Publicado: (2017)

7‐Epitaxol induces apoptosis in cisplatin‐resistant head and neck squamous cell carcinoma via suppression of AKT and MAPK signalling
por: Yang, Hui‐Ju, et al.
Publicado: (2022)

Sodium Danshensu Inhibits Oral Cancer Cell Migration and Invasion by Modulating p38 Signaling Pathway
por: Kumar, V. Bharath, et al.
Publicado: (2020)

Semilicoisoflavone B Induces Apoptosis of Oral Cancer Cells by Inducing ROS Production and Downregulating MAPK and Ras/Raf/MEK Signaling
por: Hsieh, Ming-Ju, et al.
Publicado: (2023)

Dehydrocrenatidine extracted from Picrasma quassioides induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways
por: Hsieh, Ming-Chang, et al.
Publicado: (2021)

Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial-mesenchymal transition and inhibition of MMP-2
por: Chuang, Yi-Ching, et al.
Publicado: (2021)

Coronarin D induces reactive oxygen species-mediated cell death in human nasopharyngeal cancer cells through inhibition of p38 MAPK and activation of JNK
por: Chen, Jui-Chieh, et al.
Publicado: (2017)

Chrysosplenol D Triggers Apoptosis through Heme Oxygenase-1 and Mitogen-Activated Protein Kinase Signaling in Oral Squamous Cell Carcinoma
por: Hsieh, Ming-Ju, et al.
Publicado: (2021)

Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogen-activated protein kinase pathways in vitro and in vivo
por: Chen, Jui-Chieh, et al.
Publicado: (2016)

Association of KMT2C Genetic Variants with the Clinicopathologic Development of Oral Cancer
por: Shieu, Mu-Kuei, et al.
Publicado: (2022)

Picrasidine I Triggers Heme Oxygenase-1-Induced Apoptosis in Nasopharyngeal Carcinoma Cells via ERK and Akt Signaling Pathways
por: Ho, Hsin-Yu, et al.
Publicado: (2022)

FAM13A polymorphisms are associated with a specific susceptibility to clinical progression of oral cancer in alcohol drinkers
por: Hsieh, Ming-Ju, et al.
Publicado: (2023)

Sulforaphane suppresses oral cancer cell migration by regulating cathepsin S expression
por: Chen, Chang-Tai, et al.
Publicado: (2018)

Asiatic Acid, Extracted from Centella asiatica and Induces Apoptosis Pathway through the Phosphorylation p38 Mitogen-Activated Protein Kinase in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells
por: Liu, Yen-Tze, et al.
Publicado: (2020)

Picrasidine J, a Dimeric β-Carboline-Type Alkaloid from Picrasma quassioides, Inhibits Metastasis of Head and Neck Squamous Cell Carcinoma
por: Ho, Hsin-Yu, et al.
Publicado: (2023)

Pinostilbene Hydrate Inhibits the Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Downregulating MMP-2 Expression and Suppressing Epithelial–Mesenchymal Transition Through the Mitogen-Activated Protein Kinase Signaling Pathways
por: Tseng, Pao-Yu, et al.
Publicado: (2019)

Overexpression of Lipocalin-2 Inhibits Proliferation and Invasiveness of Human Glioblastoma Multiforme Cells by Activating ERK Targeting Cathepsin D Expression
por: Hsieh, Yi-Hsien, et al.
Publicado: (2021)

Functional FGFR4 Gly388Arg polymorphism contributes to oral squamous cell carcinoma susceptibility
por: Chou, Chia-Hsuan, et al.
Publicado: (2017)

Nordalbergin Exerts Anti-Neuroinflammatory Effects by Attenuating MAPK Signaling Pathway, NLRP3 Inflammasome Activation and ROS Production in LPS-Stimulated BV2 Microglia
por: Lo, Jung, et al.
Publicado: (2023)

Dehydrocrenatidine Induces Liver Cancer Cell Apoptosis by Suppressing JNK-Mediated Signaling
por: Velmurugan, Bharath Kumar, et al.
Publicado: (2022)

Spinal cord infarction during physical exertion due to polycythemia vera and aortoiliac occlusive disease: A case report
por: Lin, Wei-Pin, et al.
Publicado: (2018)

Hispolon suppresses metastasis via autophagic degradation of cathepsin S in cervical cancer cells
por: Hsin, Min-Chieh, et al.
Publicado: (2017)

Exertional heat stroke on fertility, erectile function, and testicular morphology in male rats
por: Lin, Pei-Hsuan, et al.
Publicado: (2021)

Klotho Exerts an Emerging Role in Cytokinesis
por: Sun, Chiao-Yin, et al.
Publicado: (2020)

Spinal Cathepsin S promotes visceral hypersensitivity via FKN/CX3CR1/p38 MAPK signaling pathways
por: Sun, Pei, et al.
Publicado: (2023)

Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2
por: Chen, Jian-Ming, et al.
Publicado: (2020)

Cathepsin B Expression and the Correlation with Clinical Aspects of Oral Squamous Cell Carcinoma
por: Yang, Wei-En, et al.
Publicado: (2016)

Cathepsin-L Secreted by High-Quality Bovine Embryos Exerts an Embryotrophic Effect In Vitro
por: Raes, Annelies, et al.
Publicado: (2023)

Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways
por: Chen, Yu-An, et al.
Publicado: (2018)

Nobiletin Promotes Megakaryocytic Differentiation through the MAPK/ERK-Dependent EGR1 Expression and Exerts Anti-Leukemic Effects in Human Chronic Myeloid Leukemia (CML) K562 Cells
por: Yen, Jui-Hung, et al.
Publicado: (2020)

Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death
por: Dai, Jialin, et al.
Publicado: (2021)

Tamm-Horsfall Glycoprotein Enhances PMN Phagocytosis by Binding to Cell Surface-Expressed Lactoferrin and Cathepsin G That Activates MAP Kinase Pathway
por: Siao, Syue-Cian, et al.
Publicado: (2011)

Glucose Metabolites Exert Opposing Roles in Tumor Chemoresistance
por: Huang, Chung-Yen, et al.
Publicado: (2019)

Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway
por: Chen, I-Hsuan, et al.
Publicado: (2019)

Characterization in Potent Modulation on Voltage-Gated Na(+) Current Exerted by Deltamethrin, a Pyrethroid Insecticide
por: Lin, Mao-Hsun, et al.
Publicado: (2022)

Association between hyperglycaemic crisis and long-term major adverse cardiovascular events: a nationwide population-based, propensity score-matched, cohort study
por: Chang, Li-Hsin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vc6omio19it6vm9jp1se2r79rn