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Intra-Tumoral Genomic Heterogeneity in Rectal Cancer: Mutational Status Is Dependent on Preoperative Biopsy Depth and Location

SIMPLE SUMMARY: A subset of patients with rectal cancer are treated before surgery with chemoradiation. Unfortunately, this neoadjuvant chemoradiotherapy does not have the preferred effect of tumor downstaging in all patients, but does bring substantial side effects and possible complications. A pre...

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Detalles Bibliográficos
Autores principales:	Vuijk, Floris A., van de Water, Carlijn, Lent-van Vliet, Shannon, van der Valk, Maxime J. M., Simmer, Femke, van de Velde, Cornelis J. H., Vahrmeijer, Alexander L., Nagtegaal, Iris D., Hilling, Denise E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125993/ https://www.ncbi.nlm.nih.gov/pubmed/34065112 http://dx.doi.org/10.3390/cancers13092271

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