Cargando…

Allogenic Stem Cell Transplantation Abrogates Negative Impact on Outcome of AML Patients with KMT2A Partial Tandem Duplication

SIMPLE SUMMARY: Acute myeloid leukemia refers to a large group of diseases that can be further defined by their genetic modifications. A specific alteration called KMT2A-PTD has been previously found in 5% of newly diagnosed acute myeloid leukemia cases. This work aimed to provide specific insight i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antherieu, Gabriel, Bidet, Audrey, Huet, Sarah, Hayette, Sandrine, Migeon, Marina, Boureau, Lisa, Sujobert, Pierre, Thomas, Xavier, Ghesquières, Hervé, Pigneux, Arnaud, Heiblig, Mael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126020/ https://www.ncbi.nlm.nih.gov/pubmed/34068470 http://dx.doi.org/10.3390/cancers13092272

Ejemplares similares

Impact of Age on Poly(ADP-Ribose) Polymerase Inhibitor (PARPi)-Induced Lymphopenia: A Scoping Review of the Literature and Internal Analysis of a Retrospective Database
por: Antherieu, Gabriel, et al.
Publicado: (2023)

The Impact of DNMT3A Status on NPM1 MRD Predictive Value and Survival in Elderly AML Patients Treated Intensively
por: Heiblig, Maël, et al.
Publicado: (2021)

Performances of Targeted RNA Sequencing for the Analysis of Fusion Transcripts, Gene Mutation, and Expression in Hematological Malignancies
por: Hayette, Sandrine, et al.
Publicado: (2021)

How to Transform an Exceptional Case Report Into a Therapy: Following the Frog Out of the Box
por: Heiblig, Maël, et al.
Publicado: (2021)

Allelic complexity of KMT2A partial tandem duplications in acute myeloid leukemia and myelodysplastic syndromes
por: Tsai, Harrison K., et al.
Publicado: (2022)

Allogeneic hematopoietic stem cell transplantation at the first remission for younger adults with FLT3‐internal tandem duplication AML: The JALSG AML209‐FLT3‐SCT study
por: Kawashima, Naomi, et al.
Publicado: (2020)

Major Molecular Response Achievement in CML Patients Can Be Predicted by BCR-ABL1/ABL1 or BCR-ABL1/GUS Ratio at an Earlier Time Point of Follow-Up than Currently Recommended
por: Huet, Sarah, et al.
Publicado: (2014)

Prognostic Value of Genetic Alterations in Elderly Patients with Acute Myeloid Leukemia: A Single Institution Experience
por: Heiblig, Maël, et al.
Publicado: (2019)

Class I/Class II HLA Evolutionary Divergence Ratio Is an Independent Marker Associated With Disease-Free and Overall Survival After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia
por: Daull, Anne-Marie, et al.
Publicado: (2022)

Successful allogeneic hematopoietic stem cell transplantation in patients with VEXAS syndrome: a 2-center experience
por: Diarra, Ava, et al.
Publicado: (2022)

What Does This Mutation Mean? The Tools and Pitfalls of Variant Interpretation in Lymphoid Malignancies
por: Guillermin, Yann, et al.
Publicado: (2018)

Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications
por: Döhner, Hartmut, et al.
Publicado: (2022)

Maintenance of elderly AML patients with androgens
por: Pigneux, Arnaud, et al.
Publicado: (2017)

UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome
por: Georgi, Julia-Annabell, et al.
Publicado: (2023)

KMT2A-MLLT3 AML Masquerading as JMML may Disguise Fatal Leukemia
por: Saad, Ashraf Abdullah, et al.
Publicado: (2019)

Acute Promyelocytic Leukemia
por: Thomas, Xavier, et al.
Publicado: (2020)

Early detection of WT1 measurable residual disease identifies high-risk patients, independent of transplantation in AML
por: Lambert, Juliette, et al.
Publicado: (2021)

The Partial Duplication of the 5′ Segment of KMT2A Revealed KMT2A-MLLT10 Rearrangement in a Boy with Acute Myeloid Leukemia
por: Fukushima, Hiroko, et al.
Publicado: (2017)

UBTF tandem duplications define a distinct subtype of adult de novo acute myeloid leukemia
por: Duployez, Nicolas, et al.
Publicado: (2023)

The Landscape of KMT2A-PTD AML: Concurrent Mutations, Gene Expression Signatures, and Clinical Outcome
por: Hinai, Adil S.A. Al, et al.
Publicado: (2019)

Maintenance therapy for AML after allogeneic HCT
por: Nayak, Rahul K., et al.
Publicado: (2022)

Unclassifiable Isolated Monoclonal Lymphocytosis: Comprehensive Description of a Retrospective Cohort
por: Degaud, Michaël, et al.
Publicado: (2019)

Quantitative Assessment of Vacuolization of Myeloid Precursors in VEXAS Syndrome
por: Rabut, Audrey, et al.
Publicado: (2023)

THE ABROGATION OF SHEEP ERYTHROCYTE TOLERANCE IN RATS BY MEANS OF THE TRANSFER OF ALLOGENEIC LYMPHOCYTES
por: McCullagh, Peter J.
Publicado: (1970)

Improved inference of tandem domain duplications
por: Aluru, Chaitanya, et al.
Publicado: (2021)

Bridging Strategies to Allogeneic Transplant for Older AML Patients
por: Hecker, Judith, et al.
Publicado: (2018)

Risk classification at diagnosis predicts post-HCT outcomes in intermediate-, adverse-risk, and KMT2A-rearranged AML
por: Menghrajani, Kamal, et al.
Publicado: (2022)

Bone Marrow Microenvironment-Induced Chemoprotection in KMT2A Rearranged Pediatric AML Is Overcome by Azacitidine–Panobinostat Combination
por: Lehner, Kara M., et al.
Publicado: (2023)

Plasticity in Classical Hodgkin Composite Lymphomas: A Systematic Review
por: Trecourt, Alexis, et al.
Publicado: (2022)

Midostaurin after allogeneic stem cell transplant in patients with FLT3-internal tandem duplication-positive acute myeloid leukemia
por: Maziarz, Richard T., et al.
Publicado: (2020)

Congenital leukemia of fetus with acquired AML1 gene duplication
por: Kang, Sun-Young, et al.
Publicado: (2014)

Chaetocin Abrogates the Self-Renewal of Bladder Cancer Stem Cells via the Suppression of the KMT1A–GATA3–STAT3 Circuit
por: Yang, Zhao, et al.
Publicado: (2020)

Effective tumor cell abrogation via Venetoclax-mediated BCL-2 inhibition in KMT2A-rearranged acute B-lymphoblastic leukemia
por: Richter, Anna, et al.
Publicado: (2022)

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485
por: Mims, Alice S., et al.
Publicado: (2018)

Detecting long tandem duplications in genomic sequences
por: Audemard, Eric, et al.
Publicado: (2012)

Bone Marrow Necrosis in Newly Diagnosed Acute Leukemia: Two Case Reports and Review of the Literature
por: Quintela, Adrien, et al.
Publicado: (2017)

Point Mutations in the FLT3-ITD Region Are Rare but Recurrent Alterations in Adult AML and Associated With Concomitant KMT2A-PTD
por: Stasik, Sebastian, et al.
Publicado: (2022)

Repressing HIF-1α-induced HDAC9 contributes to the synergistic effect of venetoclax and MENIN inhibitor in KMT2Ar AML
por: Ling, Qing, et al.
Publicado: (2023)

Frugal alignment-free identification of FLT3-internal tandem duplications with FiLT3r
por: Boudry, Augustin, et al.
Publicado: (2022)

The Elephant in The Room: AML Relapse Post Allogeneic Hematopoietic Cell Transplantation
por: Abou Dalle, Iman, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h9quuepjv0eko00h7rj4cb73ru