Deregulated FASN Expression in BRAF Inhibitor-Resistant Melanoma Cells Unveils New Targets for Drug Combinations

SIMPLE SUMMARY: Strategies to overcome resistance to targeted therapy represent a clinical need for metastatic melanoma. Altered lipid metabolism has been identified in the metabolic reprogramming associated with melanoma progression. Lipid metabolism genes such as fatty acid synthase (FASN) and 24-...

Descripción completa

Detalles Bibliográficos
Autores principales: Stamatakos, Serena, Beretta, Giovanni Luca, Vergani, Elisabetta, Dugo, Matteo, Corno, Cristina, Corna, Elisabetta, Tinelli, Stella, Frigerio, Simona, Ciusani, Emilio, Rodolfo, Monica, Perego, Paola, Gatti, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126202/
https://www.ncbi.nlm.nih.gov/pubmed/34068792
http://dx.doi.org/10.3390/cancers13092284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126202/
https://www.ncbi.nlm.nih.gov/pubmed/34068792
http://dx.doi.org/10.3390/cancers13092284

Ejemplares similares