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Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer
BACKGROUND: Sipuleucel-T is a US Food and Drug Administration-approved autologous cellular immunotherapy that improves survival in patients with metastatic castration-resistant prostate cancer (mCRPC). We examined whether administering ipilimumab after sipuleucel-T could modify immune and/or clinica...
Autores principales: | Sinha, Meenal, Zhang, Li, Subudhi, Sumit, Chen, Brandon, Marquez, Jaqueline, Liu, Eric V, Allaire, Kate, Cheung, Alexander, Ng, Sharon, Nguyen, Christopher, Friedlander, Terence W, Aggarwal, Rahul, Spitzer, Matthew, Allison, James P, Small, Eric J, Sharma, Padmanee, Fong, Lawrence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126308/ https://www.ncbi.nlm.nih.gov/pubmed/33986125 http://dx.doi.org/10.1136/jitc-2020-002254 |
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