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WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility

In mammalian ovaries, immature oocytes are reserved in primordial follicles until their activation for potential ovulation. Precise control of primordial follicle activation (PFA) is essential for reproduction, but how this is achieved is unclear. Here, we show that canonical wingless-type MMTV inte...

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Detalles Bibliográficos
Autores principales: Habara, Okiko, Logan, Catriona Y., Kanai-Azuma, Masami, Nusse, Roeland, Takase, Hinako M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126407/
https://www.ncbi.nlm.nih.gov/pubmed/33914868
http://dx.doi.org/10.1242/dev.198846