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Environmental oxygen regulates astrocyte proliferation to guide angiogenesis during retinal development

Angiogenesis in the developing mammalian retina requires patterning cues from astrocytes. Developmental disorders of retinal vasculature, such as retinopathy of prematurity (ROP), involve arrest or mispatterning of angiogenesis. Whether these vascular pathologies involve astrocyte dysfunction remain...

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Detalles Bibliográficos
Autores principales: Perelli, Robin M., O'Sullivan, Matthew L., Zarnick, Samantha, Kay, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126409/
https://www.ncbi.nlm.nih.gov/pubmed/33960384
http://dx.doi.org/10.1242/dev.199418