Increased Concentrations of Circulating Soluble MHC Class I-Related Chain A (sMICA) and sMICB and Modulation of Plasma Membrane MICA Expression: Potential Mechanisms and Correlation With Natural Killer Cell Activity in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a severe autoimmune disease of unknown etiology. The major histocompatibility complex (MHC) class I-related chain A (MICA) and B (MICB) are stress-inducible cell surface molecules. MICA and MICB label malfunctioning cells for their recognition by cytotoxic lymph...

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Detalles Bibliográficos
Autores principales: Hervier, Baptiste, Ribon, Matthieu, Tarantino, Nadine, Mussard, Julie, Breckler, Magali, Vieillard, Vincent, Amoura, Zahir, Steinle, Alexander, Klein, Reinhild, Kötter, Ina, Decker, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126610/
https://www.ncbi.nlm.nih.gov/pubmed/34012432
http://dx.doi.org/10.3389/fimmu.2021.633658

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