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Centhaquine Restores Renal Blood Flow and Protects Tissue Damage After Hemorrhagic Shock and Renal Ischemia

Background: Centhaquine (CQ) (Lyfaquin(®)) is in late stage clinical development as a safe and effective first-in-class resuscitative agent for hemorrhagic shock patients (NCT02408731, NCT04056065, and NCT04045327). Acute kidney injury (AKI) is known to be associated with hemorrhagic shock. Hence, e...

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Detalles Bibliográficos
Autores principales: Ranjan, Amaresh K., Zhang, Zhong, Briyal, Seema, Gulati, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126696/
https://www.ncbi.nlm.nih.gov/pubmed/34012389
http://dx.doi.org/10.3389/fphar.2021.616253