Cargando…

Dioscorea Zingiberensis New Saponin Inhibits the Growth of Hepatocellular Carcinoma by Suppressing the Expression of Long Non-coding RNA TCONS-00026762

Background: The etiology and carcinogenesis of hepatocellular carcinoma (HCC) are associated with various risk factors. Saponins extracted from Dioscorea zingiberensis C. H. Wright exhibit antitumor activity against HCC. This study aimed to investigate the effect and the underlying mechanism of Dios...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xing, Zhou, Pingsheng, He, Keqing, Wen, Zhili, Gao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126712/ https://www.ncbi.nlm.nih.gov/pubmed/34012402 http://dx.doi.org/10.3389/fphar.2021.678620

Ejemplares similares

Evaluation of different pretreatments on microbial transformation of saponins in Dioscorea zingiberensis for diosgenin production
por: Zheng, Tianxiang, et al.
Publicado: (2014)

The genome of Dioscorea zingiberensis sheds light on the biosynthesis, origin and evolution of the medicinally important diosgenin saponins
por: Li, Yi, et al.
Publicado: (2022)

Zingiberensis Newsaponin Inhibits the Malignant Progression of Hepatocellular Carcinoma via Suppressing Autophagy Moderated by the AKR1C1-Mediated JAK2/STAT3 Pathway
por: He, Keqing, et al.
Publicado: (2021)

Identification and Characterization of a Trillin Rhamnosyltransferase From Dioscorea zingiberensis
por: Li, Jia, et al.
Publicado: (2021)

In vitro tetraploid induction and generation of tetraploids from mixoploids in Dioscorea zingiberensis
por: Huang, He-Ping, et al.
Publicado: (2010)

Comparative Transcriptome Analysis Identifies Putative Genes Involved in Dioscin Biosynthesis in Dioscorea zingiberensis
por: Li, Jia, et al.
Publicado: (2018)

Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis
por: Hou, Lixiu, et al.
Publicado: (2021)

Effects of Polysaccharide Elicitors from Endophytic Fusarium oxysporium Dzf17 on Growth and Diosgenin Production in Cell Suspension Culture of Dioscorea zingiberensis
por: Li, Peiqin, et al.
Publicado: (2011)

In situ pressurized biphase acid hydrolysis, a promising approach to produce bioactive diosgenin from the tubers of Dioscorea Zingiberensis
por: Yang, Huan, et al.
Publicado: (2015)

The Functional Characterization of DzCYP72A12-4 Related to Diosgenin Biosynthesis and Drought Adaptability in Dioscorea zingiberensis
por: Wang, Weipeng, et al.
Publicado: (2023)

One compound of saponins from Disocorea zingiberensis protected against experimental acute pancreatitis by preventing mitochondria-mediated necrosis
por: Zhang, Rui, et al.
Publicado: (2016)

Enhancement of Diosgenin Production in Dioscorea zingiberensis Cell Cultures by Oligosaccharides from Its Endophytic Fungus Fusarium oxysporum Dzf17
por: Li, Peiqin, et al.
Publicado: (2011)

Steroidal Saponins Isolated from the Rhizome of Dioscorea tokoro Inhibit Cell Growth and Autophagy in Hepatocellular Carcinoma Cells
por: Okubo, Shinya, et al.
Publicado: (2021)

Enhancement of Diepoxin ζ Production by Yeast Extract and Its Fractions in Liquid Culture of Berkleasmium-Like Endophytic Fungus Dzf12 from Dioscorea zingiberensis
por: Zhao, Jianglin, et al.
Publicado: (2011)

Saikosaponin A, a Triterpene Saponin, Suppresses Angiogenesis and Tumor Growth by Blocking VEGFR2-Mediated Signaling Pathway
por: Zhang, Pan, et al.
Publicado: (2021)

Long non-coding RNA TCONS_00000200 as a non-invasive biomarker in patients with intracranial aneurysm
por: Wu, Chenghan, et al.
Publicado: (2019)

Enhancement of Palmarumycin C(12 )and C(13) Production in Liquid Culture of the Endophytic Fungus Berkleasmium sp. Dzf12 by Oligosaccharides from Its Host Plant Dioscorea zingiberensis
por: Li, Yan, et al.
Publicado: (2012)

Prevention Effect of Protopanaxadiol-Type Saponins Saponins and Protopanaxatriol-Type Saponins on Myelosuppression Mice Induced by Cyclophosphamide
por: Zhang, He, et al.
Publicado: (2022)

Metformin Suppresses Hypopharyngeal Cancer Growth by Epigenetically Silencing Long Non-coding RNA SNHG7 in FaDu Cells
por: Wu, Ping, et al.
Publicado: (2019)

Total saponin of Dioscoreae hypoglaucae rhizoma ameliorates streptozotocin-induced diabetic nephropathy
por: Guo, Changrun, et al.
Publicado: (2016)

Study of Saponin Components after Biotransformation of Dioscorea nipponica by Endophytic Fungi C39
por: Huang, Nannan, et al.
Publicado: (2022)

Gleditsia Saponin C Induces A549 Cell Apoptosis via Caspase-Dependent Cascade and Suppresses Tumor Growth on Xenografts Tumor Animal Model
por: Cheng, Ye, et al.
Publicado: (2018)

Potential of Neglected and Underutilized Yams (Dioscorea spp.) for Improving Nutritional Security and Health Benefits
por: Padhan, Bandana, et al.
Publicado: (2020)

Saponins of ginseng products: a review of their transformation in processing
por: Ye, Xian-Wen, et al.
Publicado: (2023)

Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma
por: Yang, Gui-Ya, et al.
Publicado: (2021)

Diosgenin From Dioscorea Nipponica Rhizoma Against Graves’ Disease—On Network Pharmacology and Experimental Evaluation
por: Xin, Jingxin, et al.
Publicado: (2022)

Design of bilayer tablets using modified Dioscorea starches as novel excipients for immediate and sustained release of aceclofenac sodium
por: Okunlola, Adenike
Publicado: (2015)

Detoxification technology and mechanism of processing with Angelicae sinensis radix in reducing the hepatotoxicity induced by rhizoma Dioscoreae bulbiferae in vivo
por: Song, Lingling, et al.
Publicado: (2022)

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
por: Peng, Ming, et al.
Publicado: (2018)

Hepatoprotective Effect of Steroidal Glycosides From Dioscorea villosa on Hydrogen Peroxide-Induced Hepatotoxicity in HepG2 Cells
por: Siddiqui, Maqsood A., et al.
Publicado: (2018)

Antifungal Effects of Saponin Extract from Rhizomes of Dioscorea panthaica Prain et Burk against Candida albicans
por: Yang, Longfei, et al.
Publicado: (2018)

A novel lncRNA, TCONS_00006195, represses hepatocellular carcinoma progression by inhibiting enzymatic activity of ENO1
por: Yu, Songman, et al.
Publicado: (2018)

Cumingianoside A, a Phyto-Triterpenoid Saponin Inhibits Acquired BRAF Inhibitor Resistant Melanoma Growth via Programmed Cell Death
por: Cvetanova, Biljana, et al.
Publicado: (2019)

Development of an Oriental Medicine Discrimination Method through Analysis of Steroidal Saponins in Dioscorea nipponica Makino and Their Anti-Osteosarcoma Effects
por: Hwang, Joo Tae, et al.
Publicado: (2019)

Effect of Panax notoginseng Saponins and Major Anti-Obesity Components on Weight Loss
por: Zhang, Xuelian, et al.
Publicado: (2021)

Progress on the efficacy and mechanism of action of panax ginseng monomer saponins treat toxicity
por: Wang, Xinyi, et al.
Publicado: (2022)

The pharmacology and mechanisms of platycodin D, an active triterpenoid saponin from Platycodon grandiflorus
por: Xie, Long, et al.
Publicado: (2023)

Role of ferroptosis and its non-coding RNA regulation in hepatocellular carcinoma
por: Yang, Lei, et al.
Publicado: (2023)

Dioscorea spp. (A Wild Edible Tuber): A Study on Its Ethnopharmacological Potential and Traditional Use by the Local People of Similipal Biosphere Reserve, India
por: Kumar, Sanjeet, et al.
Publicado: (2017)

Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway
por: Lu, Qin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_eo9e7gem5pm67ggt5mn750a9fo