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DNA-inspired nanomaterials for enhanced endosomal escape

To realize RNA interference (RNAi) therapeutics, it is necessary to deliver therapeutic RNAs (such as small interfering RNA or siRNA) into cell cytoplasm. A major challenge of RNAi therapeutics is the endosomal entrapment of the delivered siRNA. In this study, we developed a family of delivery vehic...

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Detalles Bibliográficos
Autores principales:	Lee, Jinhyung, Sands, Ian, Zhang, Wuxia, Zhou, Libo, Chen, Yupeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Physical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126792/ https://www.ncbi.nlm.nih.gov/pubmed/33941681 http://dx.doi.org/10.1073/pnas.2104511118

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