Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex

Mostrar otras versiones (1)

Backtracking, the reverse motion of the transcriptase enzyme on the nucleic acid template, is a universal regulatory feature of transcription in cellular organisms but its role in viruses is not established. Here we present evidence that backtracking extends into the viral realm, where backtracking...

Descripción completa

Detalles Bibliográficos
Autores principales: Malone, Brandon, Chen, James, Wang, Qi, Llewellyn, Eliza, Choi, Young Joo, Olinares, Paul Dominic B., Cao, Xinyun, Hernandez, Carolina, Eng, Edward T., Chait, Brian T., Shaw, David E., Landick, Robert, Darst, Seth A., Campbell, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126829/
https://www.ncbi.nlm.nih.gov/pubmed/33883267
http://dx.doi.org/10.1073/pnas.2102516118
Mostrar todas las versiones(2)

Ejemplares similares