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Delineating the heterogeneity of matrix-directed differentiation toward soft and stiff tissue lineages via single-cell profiling

Mesenchymal stromal/stem cells (MSCs) form a heterogeneous population of multipotent progenitors that contribute to tissue regeneration and homeostasis. MSCs assess extracellular elasticity by probing resistance to applied forces via adhesion, cytoskeletal, and nuclear mechanotransducers that direct...

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Detalles Bibliográficos
Autores principales: Brielle, Shlomi, Bavli, Danny, Motzik, Alex, Kan-Tor, Yoav, Sun, Xue, Kozulin, Chen, Avni, Batia, Ram, Oren, Buxboim, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126831/
https://www.ncbi.nlm.nih.gov/pubmed/33941688
http://dx.doi.org/10.1073/pnas.2016322118